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ENZYME entry: EC 184.108.40.206
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|[Butirosin acyl-carrier protein]--L-glutamate ligase.
|[BtrI acyl-carrier protein]--L-glutamate ligase.|
- ATP + L-glutamate + [BtrI acyl-carrier protein] <=> ADP + phosphate + L-glutamyl-[BtrI acyl-carrier protein]
- ATP + L-glutamate + 4-amino butanoyl-[BtrI acyl-carrier protein] <=> ADP + phosphate + 4-(L-gamma-glutamylamino)butanoyl-[BtrI acyl-carrier protein]
|Mn(2+) or Mg(2+).
- Catalyzes two steps in the biosynthesis of the side chain of the
aminoglycoside antibiotics of the butirosin family.
- The enzyme adds one molecule of L-glutamate to a dedicated acyl-
carrier protein, and following decarboxylation of the product by
EC 220.127.116.11, adds a second L-glutamate molecule.
|PRIAM enzyme-specific profiles||18.104.22.168|
|KEGG Ligand Database for Enzyme Nomenclature||22.214.171.124|
|IUBMB Enzyme Nomenclature||126.96.36.199|
|MEDLINE||Find literature relating to 188.8.131.52|
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entries corresponding to 6.2.1.-
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