ID 6.2.1.40 DE 4-hydroxybutyrate--CoA ligase (AMP-forming). AN 4-hydroxybutyrate--CoA ligase. AN 4-hydroxybutyrate-CoA synthetase. CA 4-hydroxybutanoate + ATP + CoA = 4-hydroxybutanoyl-CoA + AMP + CA diphosphate. CC -!- Isolated from the archaeon Metallosphaera sedula. CC -!- Involved in the 3-hydroxypropanoate/4-hydroxybutanoate cycle. cf. CC EC 6.2.1.56. DR A4YDT1, HBCL1_METS5; A4YDR9, HBCL2_METS5; //