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ENZYME

ENZYME entry: EC 6.2.1.44

Accepted Name
3-(methylthio)propionyl--CoA ligase
Alternative Name(s)
3-methylmercaptopropionyl-CoA ligase
methylmercaptopropionate-coenzyme A ligase
MMPA-CoA ligase
Reaction catalysed
3-(methylsulfanyl)propanoate + ATP + CoA <=> 3-(methylsulfanyl)propanoyl-CoA + AMP + diphosphate
Comment(s)
  • The enzyme is part of a dimethylsulfoniopropanoate demethylation pathway in the marine bacteria Ruegeria pomeroyi and Pelagibacter ubique.
  • It also occurs in some nonmarine bacteria capable of metabolizing dimethylsulfoniopropionate (e.g. Burkholderia thailandensis, Pseudomonas aeruginosa, and Silicibacter lacuscaerulensis).
Cross-references
BRENDA6.2.1.44
EC2PDB6.2.1.44
ExplorEnz6.2.1.44
PRIAM enzyme-specific profiles6.2.1.44
KEGG Ligand Database for Enzyme Nomenclature6.2.1.44
IUBMB Enzyme Nomenclature6.2.1.44
IntEnz6.2.1.44
MEDLINEFind literature relating to 6.2.1.44
MetaCyc6.2.1.44
Rhea expert-curated reactions6.2.1.44
UniProtKB/Swiss-Prot
P0DX84, DMDB_RUELIQ5LRT0, DMDB_RUEPO

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