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ENZYME

ENZYME entry: EC 6.2.1.n2

Accepted Name
amino acid--[acyl-carrier-protein] ligase
Reaction catalysed
an L-alpha-amino acid + ATP + holo-[ACP] <=> AMP + an L-alpha-aminoacyl-[ACP] + diphosphate
Comment(s)
  • Catalyzes the ATP-dependent activation of L-alanine, and to a lesser extent of L-glycine and L-serine, and their transfer to the phosphopantetheine cofactor covalently attached to a vicinal carrier protein.
  • May participate in nonribosomal peptide synthesis or related processes.
  • L-proline and L-glutamate are very poor substrates whereas D-amino acids are not substrates for ATP-dependent activation.
  • Does not display tRNA aminoacylation activity.
Cross-references
UniProtKB/Swiss-Prot
Q89VT8, AACL1_BRADUQ89GR3, AACL2_BRADUQ7CWR3, AACL_AGRFC

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-