ID   6.3.1.20
DE   lipoate--protein ligase.
AN   lipoate protein ligase.
AN   lipoate-protein ligase A.
AN   LPL.
CA   (R)-lipoate + ATP + L-lysyl-[lipoyl-carrier protein] = AMP + diphosphate
CA   + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein].
CC   -!- This enzyme participates in lipoate salvage, and is responsible for
CC       lipoylation in the presence of exogenous lipoic acid.
CC   -!- The enzyme attaches lipoic acid to the lipoyl domains of certain key
CC       enzymes involved in oxidative metabolism, including pyruvate
CC       dehydrogenase (E2 domain), 2-oxoglutarate dehydrogenase (E2 domain),
CC       the branched-chain 2-oxoacid dehydrogenases and the glycine cleavage
CC       system (H protein).
CC   -!- Lipoylation is essential for the function of these enzymes.
CC   -!- The enzyme can also use octanoate instead of lipoate.
CC   -!- Formerly EC 2.7.7.63.
DR   Q8IEG9, LIPLA_PLAF7;  A0A0H3JR16, LPLA1_STAAM;  A0A0H3JX98, LPLA2_STAAM;
DR   P0DN72, LPLA2_STRPG;  Q9HKT2, LPLAC_THEAC;  Q9HKT1, LPLAN_THEAC;
DR   A0KMH0, LPLA_AERHH ;  Q9Y9E6, LPLA_AERPE ;  A4SQ09, LPLA_AERS4 ;
DR   P60809, LPLA_BDEBA ;  Q7VR65, LPLA_BLOFL ;  Q492U9, LPLA_BLOPB ;
DR   A8ALX2, LPLA_CITK8 ;  A7MIG6, LPLA_CROS8 ;  A7ZVS8, LPLA_ECO24 ;
DR   B7UR14, LPLA_ECO27 ;  B7MNJ3, LPLA_ECO45 ;  B7LEN2, LPLA_ECO55 ;
DR   P60776, LPLA_ECO57 ;  B7NW66, LPLA_ECO7I ;  B7MTD2, LPLA_ECO81 ;
DR   B7LXU8, LPLA_ECO8A ;  C4ZT68, LPLA_ECOBW ;  B1XFJ6, LPLA_ECODH ;
DR   A8A8B4, LPLA_ECOHS ;  A1AJV3, LPLA_ECOK1 ;  Q0T8S7, LPLA_ECOL5 ;
DR   Q8FA49, LPLA_ECOL6 ;  B1IS33, LPLA_ECOLC ;  P32099, LPLA_ECOLI ;
DR   B7NH54, LPLA_ECOLU ;  B6I6N3, LPLA_ECOSE ;  B1LEJ1, LPLA_ECOSM ;
DR   Q1R257, LPLA_ECOUT ;  A4W6A2, LPLA_ENT38 ;  B7LNS6, LPLA_ESCF3 ;
DR   B5Y273, LPLA_KLEP3 ;  A6TI00, LPLA_KLEP7 ;  P47512, LPLA_MYCGE ;
DR   P75394, LPLA_MYCPN ;  C6DKP5, LPLA_PECCP ;  Q1QEC2, LPLA_PSYCK ;
DR   B5F534, LPLA_SALA4 ;  A9MRA3, LPLA_SALAR ;  Q57G36, LPLA_SALCH ;
DR   B5FTD0, LPLA_SALDC ;  B5R2K1, LPLA_SALEP ;  B5R9V4, LPLA_SALG2 ;
DR   B4TH09, LPLA_SALHS ;  B4T4I0, LPLA_SALNS ;  Q5PK29, LPLA_SALPA ;
DR   A9N7E6, LPLA_SALPB ;  C0Q7M8, LPLA_SALPC ;  B5BAK2, LPLA_SALPK ;
DR   B4TU46, LPLA_SALSV ;  Q8Z0U0, LPLA_SALTI ;  Q8ZJV1, LPLA_SALTY ;
DR   O13629, LPLA_SCHPO ;  A8GDS3, LPLA_SERP5 ;  B2TZR8, LPLA_SHIB3 ;
DR   Q31SV2, LPLA_SHIBS ;  Q327K9, LPLA_SHIDS ;  Q3YU08, LPLA_SHISS ;
DR   A5F8E4, LPLA_VIBC3 ;  Q9KS71, LPLA_VIBCH ;  C3LM83, LPLA_VIBCM ;
DR   B3LQ66, LPLA_YEAS1 ;  B5VLD2, LPLA_YEAS6 ;  A6ZPT1, LPLA_YEAS7 ;
DR   P47051, LPLA_YEAST ;  A1JPK8, LPLA_YERE8 ;  A7FHI0, LPLA_YERP3 ;
DR   Q1C748, LPLA_YERPA ;  B2K5K7, LPLA_YERPB ;  Q8ZDY2, LPLA_YERPE ;
DR   A9R087, LPLA_YERPG ;  Q1CII3, LPLA_YERPN ;  A4TIN0, LPLA_YERPP ;
DR   Q66A10, LPLA_YERPS ;  B1JJ36, LPLA_YERPY ;  O07608, LPLJ_BACSU ;
//