ENZYME entry: EC 6.3.1.9
| Accepted Name |
|---|
| Trypanothione synthase.
|
| Alternative Name(s) |
|---|
| TSR synthetase. |
| Reaction catalysed |
|---|
| Gamma-L-glutamyl-L-cysteinyl-glycine + N(1)-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ATP <=> N(1),N(8)-bis-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate |
| Cofactor(s) |
|---|
| Magnesium.
|
| Comment(s) |
|---|
| Involved in the synthesis of trypanothione in trypanosomatids.
|
| Cross-references |
|---|
| PROSITE | PDOC50975 |
| BRENDA | 6.3.1.9 |
| EC2PDB | 6.3.1.9 |
| ExplorEnz | 6.3.1.9 |
| PRIAM enzyme-specific profiles | 6.3.1.9 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.3.1.9 |
| IUBMB Enzyme Nomenclature | 6.3.1.9 |
| IntEnz | 6.3.1.9 |
| MEDLINE | Find literature relating to 6.3.1.9 |
| MetaCyc | 6.3.1.9 |
| UniProtKB/Swiss-Prot |
|
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