ID   6.3.2.38
DE   N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase.
AN   N(alpha)-citryl-N(epsilon)-acetyl-N(epsilon)-hydroxylysine synthase.
CA   ATP + citrate + N(6)-acetyl-N(6)-hydroxy-L-lysine = AMP + diphosphate +
CA   H(+) + N(2)-citryl-N(6)-acetyl-N(6)-hydroxy-L-lysine.
CC   -!- Requires Mg(2+).
CC   -!- The enzyme is involved in the biosynthesis of aerobactin,
CC       a dihydroxamate siderophore.
CC   -!- It belongs to a class of siderophore synthases known as type A
CC       nonribosomal peptide synthase-independent synthases (NIS).
CC   -!- Type A enzymes are responsible for the formation of amide or ester
CC       bonds between polyamines or amino alcohols and a prochiral carboxyl
CC       group of citrate.
CC   -!- The enzyme is believed to form an adenylate intermediate prior to
CC       ligation.
CC   -!- Formerly EC 6.3.2.27.
DR   Q47316, IUCA_ECOLX ;  Q76BS7, IUCA_VIBMI ;
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