ID 6.3.2.47 DE dapdiamide synthase. AN dapdiamide A synthase. CA (1) 3-[[[(2R,3R)-3-carboxyoxiran-2-yl]carbonyl]amino]-L-alanine + ATP + CA L-valine = ADP + dapdiamide E + H(+) + phosphate. CA (2) ATP + L-valine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate = ADP + CA dapdiamide A + H(+) + phosphate. CA (3) ATP + L-isoleucine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate = CA ADP + dapdiamide B + H(+) + phosphate. CA (4) ATP + L-leucine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate = ADP + CA dapdiamide C + H(+) + phosphate. CC -!- The enzyme, characterized from the bacterium Pantoea agglomerans, CC is involved in biosynthesis of dapdiamide tripeptide antibiotics, CC a family of fumaramoyl- and epoxysuccinamoyl-peptides named for the CC presence of an (S)-2,3-diaminopropanoate (DAP) moiety and two amide CC linkages in their scaffold. DR E2JA31, DDAF_ENTAG ; //