ENZYME entry: EC 6.3.4.6
| Accepted Name |
|---|
| Urea carboxylase.
|
| Alternative Name(s) |
|---|
| ATP--urea amidolyase. |
| UALase. |
| UCA. |
| Urea amidolyase. |
| Urea carboxylase (hydrolyzing). |
| Urease (ATP-hydrolyzing). |
| Reaction catalysed |
|---|
| ATP + urea + HCO(3)(-) <=> ADP + phosphate + urea-1-carboxylate |
| Cofactor(s) |
|---|
| Biotin.
|
| Comment(s) |
|---|
- The Saccharomyces cerevisiae enzyme (but not that from green algae)
also catalyzes the reaction of EC 3.5.1.54, thus bringing about the
hydrolysis of urea to CO(2) and NH(3).
- The enzyme from the prokaryotic bacterium Oleomonas sagaranensis can
also use acetamide and formamide as substrates.
- Formerly EC 3.5.1.45.
|
| Cross-references |
|---|
| PROSITE | PDOC00167 ; PDOC00676 ; PDOC50975 ; PDOC50979 |
| BRENDA | 6.3.4.6 |
| EC2PDB | 6.3.4.6 |
| ExplorEnz | 6.3.4.6 |
| PRIAM enzyme-specific profiles | 6.3.4.6 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.3.4.6 |
| IUBMB Enzyme Nomenclature | 6.3.4.6 |
| IntEnz | 6.3.4.6 |
| MEDLINE | Find literature relating to 6.3.4.6 |
| MetaCyc | 6.3.4.6 |
| UniProtKB/Swiss-Prot |
|
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