ENZYME entry: EC 6.3.5.10

Accepted Name
Adenosylcobyric acid synthase (glutamine-hydrolyzing).
Alternative Name(s)
5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase.
Ado-cobyric acid synthase (glutamine hydrolyzing).
Cobyric acid synthase.
Reaction catalysed
4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H(2)O <=> 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate
Cofactor(s)
Mg(2+).
Comment(s)
  • NH(3) can act instead of glutamine.
  • This enzyme catalyzes the four-step amidation sequence from cobyrinic acid a,c-diamide to cobyric acid via the formation of cobyrinic acid triamide, tetraamide and pentaamide intermediates.
Cross-references
BRENDA6.3.5.10
EC2PDB6.3.5.10
ExplorEnz6.3.5.10
PRIAM enzyme-specific profiles6.3.5.10
KEGG Ligand Database for Enzyme Nomenclature6.3.5.10
IUBMB Enzyme Nomenclature6.3.5.10
IntEnz6.3.5.10
MEDLINEFind literature relating to 6.3.5.10
MetaCyc6.3.5.10

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.5.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-