ID 6.3.5.13 DE lipid II isoglutaminyl synthase (glutamine-hydrolyzing). CA beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)- CA di-trans,octa-cis-undecaprenyl diphosphate + L-glutamine + ATP + H2O = CA beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)- CA di-trans,octa-cis-undecaprenyl diphosphate + L-glutamate + ADP + CA phosphate + H(+). CC -!- The enzyme complex, found in Gram-positive bacteria, consists of two CC subunits. CC -!- A glutaminase subunit (cf. EC 3.5.1.2) produces an ammonia molecule CC that is channeled to a ligase subunit, which adds it to the activated CC D-glutamate residue of lipid II, converting it to an isoglutamine CC residue. DR A0A0H2WZ38, GATD_STAAC ; A0A0H3JN63, GATD_STAAN ; Q8DNZ8, GATD_STRR6 ; DR A0A0H2WZQ7, MURT_STAAC ; A0A0H3JUU7, MURT_STAAN ; Q8DNZ9, MURT_STRR6 ; //