ENZYME entry: EC 6.3.5.3

Accepted Name
Phosphoribosylformylglycinamidine synthase.
Alternative Name(s)
FGAM synthase.
FGAM synthetase.
FGAR amidotransferase.
FGARAT.
Formylglycinamide ribotide amidotransferase.
Phosphoribosylformylglycinamidine synthetase.
Reaction catalysed
ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O <=> ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate
Cross-references
PROSITEPDOC00405
BRENDA6.3.5.3
EC2PDB6.3.5.3
ExplorEnz6.3.5.3
PRIAM enzyme-specific profiles6.3.5.3
KEGG Ligand Database for Enzyme Nomenclature6.3.5.3
IUBMB Enzyme Nomenclature6.3.5.3
IntEnz6.3.5.3
MEDLINEFind literature relating to 6.3.5.3
MetaCyc6.3.5.3
UniProtKB/Swiss-Prot
Q9M8D3, PUR4_ARATH;  Q19311, PUR4_CAEEL;  Q47XX7, PUR4_COLP3;  
Q54JC8, PUR4_DICDI;  P35421, PUR4_DROME;  Q8XA46, PUR4_ECO57;  
Q0TET1, PUR4_ECOL5;  Q8FF26, PUR4_ECOL6;  P15254, PUR4_ECOLI;  
Q1R8H7, PUR4_ECOUT;  Q4QME6, PUR4_HAEI8;  P43847, PUR4_HAEIN;  
Q2SK05, PUR4_HAHCH;  Q0I5H4, PUR4_HISS1;  O15067, PUR4_HUMAN;  
Q5QWY0, PUR4_IDILO;  Q65RJ7, PUR4_MANSM;  Q1H2I8, PUR4_METFK;  
Q5SUR0, PUR4_MOUSE;  Q1D9V4, PUR4_MYXXD;  Q5F7J4, PUR4_NEIG1;  
Q9JWC5, PUR4_NEIMA;  Q9JXK5, PUR4_NEIMB;  Q9CLW4, PUR4_PASMU;  
Q6D238, PUR4_PECAS;  Q7N1Z4, PUR4_PHOLL;  Q6LU24, PUR4_PHOPR;  
Q48LX3, PUR4_PSE14;  Q15R69, PUR4_PSEA6;  Q9HXN2, PUR4_PSEAE;  
Q4KHS6, PUR4_PSEF5;  Q3IHZ2, PUR4_PSEHT;  Q3KHL4, PUR4_PSEPF;  
Q88P16, PUR4_PSEPK;  Q886W6, PUR4_PSESM;  Q4ZX02, PUR4_PSEU2;  
Q8XYN6, PUR4_RALSO;  Q57LE6, PUR4_SALCH;  Q5PIG8, PUR4_SALPA;  
Q8Z4L6, PUR4_SALTI;  P74881, PUR4_SALTY;  O14228, PUR4_SCHPO;  
Q12PR7, PUR4_SHEDO;  Q085S1, PUR4_SHEFN;  Q8EC57, PUR4_SHEON;  
Q0HKU9, PUR4_SHESM;  Q0HX47, PUR4_SHESR;  Q31XT0, PUR4_SHIBS;  
Q32D15, PUR4_SHIDS;  Q3YYZ8, PUR4_SHISS;  Q2NS22, PUR4_SODGM;  
Q9KTN2, PUR4_VIBCH;  Q5E749, PUR4_VIBF1;  Q87RW0, PUR4_VIBPA;  
Q8DF81, PUR4_VIBVU;  Q7MN70, PUR4_VIBVY;  Q8PGR7, PUR4_XANAC;  
Q8PCQ7, PUR4_XANCP;  Q9PDF6, PUR4_XYLFA;  Q87DN2, PUR4_XYLFT;  
P38972, PUR4_YEAST;  Q1C5E7, PUR4_YERPA;  Q8ZCQ2, PUR4_YERPE;  
Q1CKD2, PUR4_YERPN;  Q667W1, PUR4_YERPS;  B0C6R3, PURL_ACAM1;  
A5G1X4, PURL_ACICJ;  B9JFQ3, PURL_AGRRK;  Q8UEB0, PURL_AGRT5;  
B9JVW2, PURL_AGRVS;  A6TLS3, PURL_ALKMQ;  B8JBS8, PURL_ANAD2;  
Q2IHC1, PURL_ANADE;  A7HIJ4, PURL_ANADF;  B4UIX7, PURL_ANASK;  
Q3M6Z4, PURL_ANAVT;  B7GFT8, PURL_ANOFW;  O67691, PURL_AQUAE;  
O28339, PURL_ARCFU;  A8I8B0, PURL_AZOC5;  A7Z249, PURL_BACA2;  
C3PBN0, PURL_BACAA;  C3L532, PURL_BACAC;  A0R8Z6, PURL_BACAH;  
Q81ZH2, PURL_BACAN;  B7JM85, PURL_BACC0;  Q73EN5, PURL_BACC1;  
B7IUV3, PURL_BACC2;  C1EV63, PURL_BACC3;  B7H4T6, PURL_BACC4;  
B7HS32, PURL_BACC7;  A7GKH8, PURL_BACCN;  B9J1K5, PURL_BACCQ;  
Q81IQ3, PURL_BACCR;  Q63GT3, PURL_BACCZ;  Q9KF57, PURL_BACHD;  
Q6HPA4, PURL_BACHK;  Q65MS8, PURL_BACLD;  A8FAM7, PURL_BACP2;  
Q5WJ86, PURL_BACSK;  P12042, PURL_BACSU;  A9VRF1, PURL_BACWK;  
A1UT47, PURL_BARBK;  Q6G335, PURL_BARHE;  Q6FZI9, PURL_BARQU;  
A9IVH5, PURL_BART1;  B2IC83, PURL_BEII9;  Q89IC0, PURL_BRADU;  
A5EMI1, PURL_BRASB;  A4YRR9, PURL_BRASO;  B2S573, PURL_BRUA1;  
Q2YNG6, PURL_BRUA2;  Q57DR8, PURL_BRUAB;  A9MAL4, PURL_BRUC2;  
C0RIH1, PURL_BRUMB;  Q8YGN1, PURL_BRUME;  A5VQ15, PURL_BRUO2;  
B0CLG4, PURL_BRUSI;  Q8G183, PURL_BRUSU;  A8MCK2, PURL_CALMQ;  
A8Z6J5, PURL_CAMC1;  A7GYY9, PURL_CAMC5;  A7I157, PURL_CAMHC;  
A8FM09, PURL_CAMJ8;  A7H373, PURL_CAMJD;  Q9PNY0, PURL_CAMJE;  
A1VZU6, PURL_CAMJJ;  Q5HUK4, PURL_CAMJR;  B9KFP6, PURL_CAMLR;  
Q3AD64, PURL_CARHZ;  Q9A5F0, PURL_CAUCR;  Q3ARU4, PURL_CHLCH;  
Q8KD17, PURL_CHLTE;  C3PIW7, PURL_CORA7;  Q9RHW9, PURL_CORAM;  
Q8FMM3, PURL_COREF;  A4QGY6, PURL_CORGB;  Q8NMI5, PURL_CORGL;  
Q4JXF0, PURL_CORJK;  B8HRP1, PURL_CYAP4;  Q9RXT4, PURL_DEIRA;  
Q833Y9, PURL_ENTFA;  Q2NAT8, PURL_ERYLH;  C4L299, PURL_EXISA;  
Q2J4M9, PURL_FRASC;  A8LCI3, PURL_FRASN;  Q5L3D2, PURL_GEOKA;  
C5D4I0, PURL_GEOSW;  A4IJX3, PURL_GEOTN;  Q7NIR9, PURL_GLOVI;  
Q5FNL0, PURL_GLUOX;  Q0BRI4, PURL_GRABC;  B9LT08, PURL_HALLT;  
Q5V2D3, PURL_HALMA;  B0R4B5, PURL_HALS3;  Q9HR49, PURL_HALSA;  
Q18JI5, PURL_HALWD;  Q7VF52, PURL_HELHP;  A8ABX6, PURL_IGNH4;  
Q28QC2, PURL_JANSC;  Q5FIV1, PURL_LACAC;  Q037U9, PURL_LACC3;  
P35852, PURL_LACCA;  Q1G9F8, PURL_LACDA;  Q049L7, PURL_LACDB;  
B2GF74, PURL_LACF3;  A8YW85, PURL_LACH4;  Q9CFE8, PURL_LACLA;  
Q9ZB06, PURL_LACLC;  A2RJW3, PURL_LACLM;  Q02Y55, PURL_LACLS;  
Q88U25, PURL_LACPL;  A5VHT8, PURL_LACRD;  B2G5B8, PURL_LACRJ;  
Q1WU59, PURL_LACS1;  Q38XW7, PURL_LACSS;  Q6ACC3, PURL_LEIXX;  
B0SB88, PURL_LEPBA;  Q04QS4, PURL_LEPBJ;  Q053V5, PURL_LEPBL;  
B0ST16, PURL_LEPBP;  Q72PR5, PURL_LEPIC;  Q8F6I3, PURL_LEPIN;  
Q03Y89, PURL_LEUMM;  Q92AN9, PURL_LISIN;  C1KW68, PURL_LISMC;  
Q71YP9, PURL_LISMF;  B8DDY8, PURL_LISMH;  Q8Y6C1, PURL_LISMO;  
A0AJM3, PURL_LISW6;  B9EAY8, PURL_MACCJ;  Q11IV2, PURL_MESSB;  
A6UX13, PURL_META3;  Q8TIT6, PURL_METAC;  Q46F25, PURL_METBF;  
Q58660, PURL_METJA;  Q8TY09, PURL_METKA;  Q8PYK1, PURL_METMA;  
A5UMW9, PURL_METS3;  A4YI68, PURL_METS5;  B8EPE8, PURL_METSB;  
Q2NEB6, PURL_METST;  O27427, PURL_METTH;  P26500, PURL_METTM;  
A0B5C7, PURL_METTP;  Q2RGU5, PURL_MOOTA;  A0QAT1, PURL_MYCA1;  
B1MHY1, PURL_MYCA9;  P0A5T9, PURL_MYCBO;  A1KGT6, PURL_MYCBP;  
C1ALD8, PURL_MYCBT;  A4T7J3, PURL_MYCGI;  B8ZSV5, PURL_MYCLB;  
Q50023, PURL_MYCLE;  Q743F0, PURL_MYCPA;  A5U0J2, PURL_MYCTA;  
P9WHL6, PURL_MYCTO;  P9WHL7, PURL_MYCTU;  A1TFE0, PURL_MYCVP;  
Q3IQL3, PURL_NATPD;  Q1QMU2, PURL_NITHX;  A6Q3E8, PURL_NITSB;  
Q3ST22, PURL_NITWN;  Q5Z2C3, PURL_NOCFA;  A1SPT8, PURL_NOCSJ;  
B2IU46, PURL_NOSP7;  Q8YR06, PURL_NOSS1;  Q2G630, PURL_NOVAD;  
Q8ES96, PURL_OCEIH;  A6X1J9, PURL_OCHA4;  A1B943, PURL_PARDP;  
A7HWB1, PURL_PARL1;  Q3B3Y0, PURL_PELLD;  Q4FLJ4, PURL_PELUB;  
A9BIH4, PURL_PETMO;  Q6KZR2, PURL_PICTO;  Q6A6C0, PURL_PROAC;  
A3PA50, PURL_PROM0;  A2BZA6, PURL_PROM1;  A8G1Z0, PURL_PROM2;  
A2C5J9, PURL_PROM3;  A2BTV9, PURL_PROM5;  Q31DI1, PURL_PROM9;  
Q7VEK9, PURL_PROMA;  Q7V9E5, PURL_PROMM;  Q7V3R5, PURL_PROMP;  
A2BNC9, PURL_PROMS;  Q46I59, PURL_PROMT;  Q9UXW6, PURL_PYRAB;  
Q8ZZJ7, PURL_PYRAE;  A4WMV7, PURL_PYRAR;  A3MXD4, PURL_PYRCJ;  
Q8U491, PURL_PYRFU;  O59621, PURL_PYRHO;  A1RQQ2, PURL_PYRIL;  
B1YBM5, PURL_PYRNV;  A9WV65, PURL_RENSM;  B3PPS1, PURL_RHIE6;  
Q2K7X0, PURL_RHIEC;  Q9KH12, PURL_RHIFH;  Q1MG23, PURL_RHIL3;  
Q98NN7, PURL_RHILO;  B5ZQU1, PURL_RHILW;  Q92PH7, PURL_RHIME;  
C3MD72, PURL_RHISN;  C0ZP44, PURL_RHOE4;  C1ATA2, PURL_RHOOB;  
Q2ITQ2, PURL_RHOP2;  Q07R72, PURL_RHOP5;  Q6N9F2, PURL_RHOPA;  
Q218N3, PURL_RHOPB;  Q13AA1, PURL_RHOPS;  B3Q7H9, PURL_RHOPT;  
Q2RWI3, PURL_RHORT;  Q3J273, PURL_RHOS4;  A4WQY3, PURL_RHOS5;  
B9KSY5, PURL_RHOSK;  Q0S766, PURL_RHOSR;  Q163V9, PURL_ROSDO;  
Q5LS98, PURL_RUEPO;  Q1GHL5, PURL_RUEST;  Q2RZ77, PURL_SALRD;  
A6U9L9, PURL_SINMW;  A7X0W1, PURL_STAA1;  A6U0N7, PURL_STAA2;  
Q2FI09, PURL_STAA3;  Q2FZJ0, PURL_STAA8;  A5IRV6, PURL_STAA9;  
Q2YX54, PURL_STAAB;  Q5HH15, PURL_STAAC;  A6QFS7, PURL_STAAE;  
P65900, PURL_STAAM;  P65901, PURL_STAAN;  Q6GI15, PURL_STAAR;  
Q6GAE4, PURL_STAAS;  A8Z1L1, PURL_STAAT;  Q8NX92, PURL_STAAW;  
B9DQ38, PURL_STACT;  Q5HQA1, PURL_STAEQ;  Q8CPN9, PURL_STAES;  
Q4L578, PURL_STAHJ;  Q49WJ3, PURL_STAS1;  Q82FW4, PURL_STRAW;  
Q9RKK5, PURL_STRCO;  Q4J8F8, PURL_SULAC;  Q30T55, PURL_SULDN;  
C3N674, PURL_SULIA;  C4KHN7, PURL_SULIK;  C3MQF3, PURL_SULIL;  
C3MW31, PURL_SULIM;  C3NH14, PURL_SULIN;  C3NEN0, PURL_SULIY;  
A6QAK6, PURL_SULNB;  Q9UX24, PURL_SULSO;  Q970V6, PURL_SULTO;  
Q67KF8, PURL_SYMTH;  Q55041, PURL_SYNE7;  Q2JQL7, PURL_SYNJA;  
Q2JI39, PURL_SYNJB;  Q5N1Y6, PURL_SYNP6;  A5GHL4, PURL_SYNPW;  
Q7UA92, PURL_SYNPX;  Q3B100, PURL_SYNS9;  Q3ANP7, PURL_SYNSC;  
P72644, PURL_SYNY3;  Q9HJA4, PURL_THEAC;  Q8DIA7, PURL_THEEB;  
Q47TL8, PURL_THEFY;  C5A4U6, PURL_THEGJ;  Q5JFL7, PURL_THEKO;  
A8F8I3, PURL_THELT;  Q9X0X3, PURL_THEMA;  B0KBQ5, PURL_THEP3;  
B0K3Q4, PURL_THEPX;  B9KZ38, PURL_THERP;  C6A0I0, PURL_THESM;  
Q72IH7, PURL_THET2;  Q5SMH8, PURL_THET8;  Q8RBK5, PURL_THETN;  
Q97BD5, PURL_THEVO;  Q83H66, PURL_TROW8;  Q83FE8, PURL_TROWT;  
Q7M9L5, PURL_WOLSU;  Q9REQ6, PURL_ZYMMO;  B0C7S1, PURQ_ACAM1;  
A6TLS2, PURQ_ALKMQ;  Q2IG97, PURQ_ANADE;  Q3MG53, PURQ_ANAVT;  
B7GFT7, PURQ_ANOFW;  O67190, PURQ_AQUAE;  O29008, PURQ_ARCFU;  
A7Z248, PURQ_BACA2;  C3PBM9, PURQ_BACAA;  C3L531, PURQ_BACAC;  
A0R8Z5, PURQ_BACAH;  Q81ZH3, PURQ_BACAN;  B7JM84, PURQ_BACC0;  
Q73EN6, PURQ_BACC1;  B7IUV2, PURQ_BACC2;  C1EV62, PURQ_BACC3;  
B7H4T5, PURQ_BACC4;  B7HS31, PURQ_BACC7;  A7GKH7, PURQ_BACCN;  
B9J1K4, PURQ_BACCQ;  Q81IQ4, PURQ_BACCR;  Q63GT4, PURQ_BACCZ;  
Q9KF58, PURQ_BACHD;  Q6HPA5, PURQ_BACHK;  Q65MS9, PURQ_BACLD;  
A8FAM6, PURQ_BACP2;  Q5WJ87, PURQ_BACSK;  P12041, PURQ_BACSU;  
A9VRF0, PURQ_BACWK;  Q6G336, PURQ_BARHE;  Q6FZJ0, PURQ_BARQU;  
Q89IB6, PURQ_BRADU;  C0ZKC5, PURQ_BREBN;  Q2YNG3, PURQ_BRUA2;  
Q57DR5, PURQ_BRUAB;  Q8YGN4, PURQ_BRUME;  Q8G180, PURQ_BRUSU;  
Q9PHZ7, PURQ_CAMJE;  Q3AD65, PURQ_CARHZ;  Q9A5F3, PURQ_CAUCR;  
Q3AS25, PURQ_CHLCH;  B3QMT1, PURQ_CHLP8;  Q8KCS5, PURQ_CHLTE;  
Q9RHX0, PURQ_CORAM;  Q8FMM2, PURQ_COREF;  Q8NMI4, PURQ_CORGL;  
Q4JXF1, PURQ_CORJK;  Q3Z9H5, PURQ_DEHE1;  Q1J2B6, PURQ_DEIGD;  
Q9RXT3, PURQ_DEIRA;  Q833Y8, PURQ_ENTFA;  B1YJ04, PURQ_EXIS2;  
C4L298, PURQ_EXISA;  Q2J4N0, PURQ_FRASC;  Q5L3D3, PURQ_GEOKA;  
C5D4H9, PURQ_GEOSW;  A4IJX2, PURQ_GEOTN;  Q7NL01, PURQ_GLOVI;  
Q5FNL1, PURQ_GLUOX;  Q9HNU2, PURQ_HALSA;  Q18FM4, PURQ_HALWD;  
Q7VFQ4, PURQ_HELHP;  Q28PA2, PURQ_JANSC;  Q1IPG4, PURQ_KORVE;  
Q5FIV0, PURQ_LACAC;  Q037U8, PURQ_LACC3;  P35851, PURQ_LACCA;  
B3WF98, PURQ_LACCB;  Q1G9F7, PURQ_LACDA;  B2GF73, PURQ_LACF3;  
Q9CFE7, PURQ_LACLA;  Q9ZB07, PURQ_LACLC;  Q88U24, PURQ_LACPL;  
A5VHT7, PURQ_LACRD;  B2G5B7, PURQ_LACRJ;  Q1WU60, PURQ_LACS1;  
Q38XW8, PURQ_LACSS;  Q6ACD4, PURQ_LEIXX;  Q72UH6, PURQ_LEPIC;  
Q8F0I2, PURQ_LEPIN;  Q92AN8, PURQ_LISIN;  C1KW69, PURQ_LISMC;  
Q71YP8, PURQ_LISMF;  B8DDY7, PURQ_LISMH;  Q8Y6C0, PURQ_LISMO;  
A0AJM4, PURQ_LISW6;  B1HTV3, PURQ_LYSSC;  Q11IV0, PURQ_MESSB;  
Q8TPF0, PURQ_METAC;  Q468N4, PURQ_METBF;  Q59042, PURQ_METJA;  
Q8TX85, PURQ_METKA;  A4G010, PURQ_METM5;  A6VIG8, PURQ_METM7;  
Q8PTB0, PURQ_METMA;  Q6M0U0, PURQ_METMP;  Q2NF29, PURQ_METST;  
O26270, PURQ_METTH;  A0B5C6, PURQ_METTP;  Q2RGU4, PURQ_MOOTA;  
P65903, PURQ_MYCBO;  O05756, PURQ_MYCLE;  Q743F9, PURQ_MYCPA;  
P9WHL4, PURQ_MYCTO;  P9WHL5, PURQ_MYCTU;  Q3IMR2, PURQ_NATPD;  
Q1QMU3, PURQ_NITHX;  Q3ST24, PURQ_NITWN;  Q5Z2C8, PURQ_NOCFA;  
Q8YU79, PURQ_NOSS1;  Q2G9J6, PURQ_NOVAD;  Q8ES97, PURQ_OCEIH;  
Q3B397, PURQ_PELLD;  Q4FLJ5, PURQ_PELUB;  Q6L0V9, PURQ_PICTO;  
Q6A6B0, PURQ_PROAC;  Q31B97, PURQ_PROM9;  Q7VC88, PURQ_PROMA;  
Q7V834, PURQ_PROMM;  Q7V1S5, PURQ_PROMP;  Q46LE9, PURQ_PROMT;  
Q9UXW5, PURQ_PYRAB;  Q8ZZJ9, PURQ_PYRAE;  Q8U492, PURQ_PYRFU;  
O59619, PURQ_PYRHO;  Q2K7X5, PURQ_RHIEC;  Q1MG27, PURQ_RHIL3;  
Q98NN0, PURQ_RHILO;  Q92PI1, PURQ_RHIME;  Q2ITP9, PURQ_RHOP2;  
Q6N376, PURQ_RHOPA;  Q218N7, PURQ_RHOPB;  Q2RWI2, PURQ_RHORT;  
Q3J4K2, PURQ_RHOS4;  Q0S774, PURQ_RHOSR;  Q167J3, PURQ_ROSDO;  
Q1AXB7, PURQ_RUBXD;  Q5LS78, PURQ_RUEPO;  Q1GGM0, PURQ_RUEST;  
Q2S567, PURQ_SALRD;  Q1GVL0, PURQ_SPHAL;  Q2FI10, PURQ_STAA3;  
Q2FZJ1, PURQ_STAA8;  Q2YX55, PURQ_STAAB;  Q5HH16, PURQ_STAAC;  
P65904, PURQ_STAAM;  P99166, PURQ_STAAN;  Q6GI16, PURQ_STAAR;  
Q6GAE5, PURQ_STAAS;  Q8NX93, PURQ_STAAW;  Q5HQA2, PURQ_STAEQ;  
Q8CPP0, PURQ_STAES;  Q4L577, PURQ_STAHJ;  Q49WJ2, PURQ_STAS1;  
Q82FW3, PURQ_STRAW;  Q9RKK6, PURQ_STRCO;  Q30TB2, PURQ_SULDN;  
Q9UX21, PURQ_SULSO;  Q67KF7, PURQ_SYMTH;  Q31Q18, PURQ_SYNE7;  
Q2JWK2, PURQ_SYNJA;  Q2JPK0, PURQ_SYNJB;  Q5N459, PURQ_SYNP6;  
Q7U831, PURQ_SYNPX;  Q3AYR1, PURQ_SYNS9;  Q3AII4, PURQ_SYNSC;  
Q55843, PURQ_SYNY3;  Q9HIM1, PURQ_THEAC;  Q8DGX5, PURQ_THEEB;  
Q5JFP4, PURQ_THEKO;  A8F8I4, PURQ_THELT;  Q9X0X2, PURQ_THEMA;  
B9KZ37, PURQ_THERP;  Q72IH9, PURQ_THET2;  Q5SI57, PURQ_THET8;  
Q8RBK6, PURQ_THETN;  Q97C36, PURQ_THEVO;  Q73MV2, PURQ_TREDE;  
Q7M9X7, PURQ_WOLSU;  Q5NMA4, PURQ_ZYMMO;  

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