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ENZYME entry: EC 6.3.5.9

Accepted Name
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing).
Reaction catalysed
2 ATP + hydrogenobyrinic acid + 2 L-glutamine + 2 H(2)O <=> 2 ADP + 2 phosphate + hydrogenobyrinic acid a,c-diamide + 2 L-glutamate
Comment(s)
This step in the aerobic biosynthesis of cobalamin generates hydrogenobyrinic acid a,c-diamide, the substrate required by EC 6.6.1.2, which adds cobalt to the macrocycle.
Cross-references
BRENDA6.3.5.9
EC2PDB6.3.5.9
ExplorEnz6.3.5.9
PRIAM enzyme-specific profiles6.3.5.9
KEGG Ligand Database for Enzyme Nomenclature6.3.5.9
IUBMB Enzyme Nomenclature6.3.5.9
IntEnz6.3.5.9
MEDLINEFind literature relating to 6.3.5.9
MetaCyc6.3.5.9
UniProtKB/Swiss-Prot
Q8UBQ8, COBB_AGRFC;  Q57CK2, COBB_BRUAB;  Q8YHU1, COBB_BRUME;  
A5VR62, COBB_BRUO2;  Q8G020, COBB_BRUSU;  P63836, COBB_MYCBO;  
P9WP96, COBB_MYCTO;  P9WP97, COBB_MYCTU;  A6X051, COBB_OCHA4;  
Q9I471, COBB_PSEAE;  P21632, COBB_PSEDE;  A4VJ35, COBB_PSEU5;  
Q98KP1, COBB_RHILO;  Q92P48, COBB_RHIME;  O68108, COBB_RHOCB;  
Q9RJ16, COBB_STRCO;  Q47T68, COBB_THEFY;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.5.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-