To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 6.4.1.7

Accepted Name
2-oxoglutarate carboxylase.
Alternative Name(s)
Carboxylating factor for ICDH.
CFI.
OGC.
Oxalosuccinate synthetase.
Reaction catalysed
ATP + 2-oxoglutarate + HCO(3)(-) <=> ADP + phosphate + oxalosuccinate
Cofactor(s)
Biotin; Mg(2+).
Comment(s)
  • It was originally thought that this enzyme was a promoting factor for the carboxylation of 2-oxoglutarate by EC 1.1.1.41, but this has since been disproved.
  • The product of the reaction is unstable and is quickly converted into isocitrate by the action of EC 1.1.1.41.
Cross-references
PROSITEPDOC00676 ; PDOC50975
BRENDA6.4.1.7
EC2PDB6.4.1.7
ExplorEnz6.4.1.7
PRIAM enzyme-specific profiles6.4.1.7
KEGG Ligand Database for Enzyme Nomenclature6.4.1.7
IUBMB Enzyme Nomenclature6.4.1.7
IntEnz6.4.1.7
MEDLINEFind literature relating to 6.4.1.7
MetaCyc6.4.1.7
UniProtKB/Swiss-Prot
D3DJ41, 2OCL_HYDTT;  D3DJ42, 2OCS_HYDTT;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-