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ENZYME

ENZYME entry: EC 7.2.2.16

Accepted Name
ABC-type ferric hydroxamate transporter
Alternative Name(s)
iron(III) hydroxamate ABC transporter
iron(III) hydroxamate transporting ATPase
Reaction catalysed
ATP + H2O + Fe(3+)-hydroxamate complex-[hydroxamate-binding protein]Side 1 <=> ADP + phosphate + Fe(3+)-hydroxamate complexSide 2 + [hydroxamate-binding protein]Side 1
Comment(s)
  • An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the import of Fe(3+)-complexed hydroxamate siderophores such as coprogen, ferrichrome and the ferric hydroxamate antibiotic, albomycin.
  • Formerly EC 3.6.3.34.
Cross-references
BRENDA7.2.2.16
EC2PDB7.2.2.16
ExplorEnz7.2.2.16
PRIAM enzyme-specific profiles7.2.2.16
KEGG Ligand Database for Enzyme Nomenclature7.2.2.16
IUBMB Enzyme Nomenclature7.2.2.16
IntEnz7.2.2.16
MEDLINEFind literature relating to 7.2.2.16
MetaCyc7.2.2.16
Rhea expert-curated reactions7.2.2.16
UniProtKB/Swiss-Prot
P49938, FHUC_BACSUP07821, FHUC_ECOLI

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