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ENZYME

ENZYME entry: EC 1.1.1.1

Accepted Name
alcohol dehydrogenase
Alternative Name(s)
aldehyde reductase
Reaction catalysed
  • a primary alcohol + NAD(+) <=> an aldehyde + H(+) + NADH
  • a secondary alcohol + NAD(+) <=> a ketone + H(+) + NADH
Comment(s)
  • Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.
  • The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
  • Formerly EC 1.1.1.32.
Cross-references
BRENDA1.1.1.1
EC2PDB1.1.1.1
ExplorEnz1.1.1.1
PRIAM enzyme-specific profiles1.1.1.1
KEGG Ligand Database for Enzyme Nomenclature1.1.1.1
IUBMB Enzyme Nomenclature1.1.1.1
IntEnz1.1.1.1
MEDLINEFind literature relating to 1.1.1.1
MetaCyc1.1.1.1
Rhea expert-curated reactions1.1.1.1
UniProtKB/Swiss-Prot
P07327, ADH1A_HUMANP28469, ADH1A_MACMUQ5RBP7, ADH1A_PONAB
P25405, ADH1A_SAAHAP25406, ADH1B_SAAHAP00327, ADH1E_HORSE
P00326, ADH1G_HUMANO97959, ADH1G_PAPHAP00328, ADH1S_HORSE
P80222, ADH1_ALLMIP30350, ADH1_ANAPLP49645, ADH1_APTAU
P06525, ADH1_ARATHP41747, ADH1_ASPFNQ17334, ADH1_CAEEL
P43067, ADH1_CANAXP85440, ADH1_CATROP14219, ADH1_CENAM
P48814, ADH1_CERCAQ70UN9, ADH1_CERCOP23991, ADH1_CHICK
P86883, ADH1_COLLIP19631, ADH1_COTJAP23236, ADH1_DROHY
P48586, ADH1_DROMNP09370, ADH1_DROMOP22246, ADH1_DROMT
P07161, ADH1_DROMUP12854, ADH1_DRONAP08843, ADH1_EMENI
A0A165U5V5, ADH1_EUPLTP26325, ADH1_GADMCQ9Z2M2, ADH1_GEOAT
Q64413, ADH1_GEOBUQ64415, ADH1_GEOKNP12311, ADH1_GEOSE
P05336, ADH1_HORVUP20369, ADH1_KLULAQ07288, ADH1_KLUMA
P00333, ADH1_MAIZEP86885, ADH1_MESAUP00329, ADH1_MOUSE
P80512, ADH1_NAJNAQ9P6C8, ADH1_NEUCRQ75ZX4, ADH1_ORYSI
Q2R8Z5, ADH1_ORYSJP12886, ADH1_PEAP22797, ADH1_PELPE
P41680, ADH1_PERMAP25141, ADH1_PETHYO00097, ADH1_PICST
Q03505, ADH1_RABITP06757, ADH1_RATP14673, ADH1_SOLTU
P80338, ADH1_STRCAP13603, ADH1_TRIRPP00330, ADH1_YEAST
Q07264, ADH1_ZEALUP20368, ADH1_ZYMMOO45687, ADH2_CAEEL
O94038, ADH2_CANALP48815, ADH2_CERCAQ70UP5, ADH2_CERCO
Q70UP6, ADH2_CERROP27581, ADH2_DROARP25720, ADH2_DROBU
P23237, ADH2_DROHYP48587, ADH2_DROMNP09369, ADH2_DROMO
P07160, ADH2_DROMUP24267, ADH2_DROWHP37686, ADH2_ECOLI
P54202, ADH2_EMENIQ24803, ADH2_ENTH1P42327, ADH2_GEOSE
P10847, ADH2_HORVUP49383, ADH2_KLULAQ9P4C2, ADH2_KLUMA
P04707, ADH2_MAIZEQ4R1E8, ADH2_ORYSIQ0ITW7, ADH2_ORYSJ
O13309, ADH2_PICSTP28032, ADH2_SOLLCP14674, ADH2_SOLTU
F2Z678, ADH2_YARLIP00331, ADH2_YEASTF8DVL8, ADH2_ZYMMA
P0DJA2, ADH2_ZYMMOP07754, ADH3_EMENIP42328, ADH3_GEOSE
P10848, ADH3_HORVUP49384, ADH3_KLULAP14675, ADH3_SOLTU
P07246, ADH3_YEASTP49385, ADH4_KLULAQ09669, ADH4_SCHPO
A6ZTT5, ADH4_YEAS7P10127, ADH4_YEASTQ6XQ67, ADH5_SACPS
P38113, ADH5_YEASTP28332, ADH6_HUMANP41681, ADH6_PERMA
Q5R7Z8, ADH6_PONABQ5XI95, ADH6_RATP40394, ADH7_HUMAN
Q64437, ADH7_MOUSEP41682, ADH7_RATP9WQC0, ADHA_MYCTO
P9WQC1, ADHA_MYCTUO31186, ADHA_RHIMEQ7U1B9, ADHB_MYCBO
P9WQC6, ADHB_MYCTOP9WQC7, ADHB_MYCTUP9WQB8, ADHD_MYCTO
P9WQB9, ADHD_MYCTUP33744, ADHE_CLOABP0A9Q8, ADHE_ECO57
P0A9Q7, ADHE_ECOLIA0A0H2ZM56, ADHE_STRP2A0A0H2URT2, ADHE_STRPN
P81600, ADHH_GADMOP72324, ADHI_CERS4Q9SK86, ADHL1_ARATH
Q9SK87, ADHL2_ARATHA1L4Y2, ADHL3_ARATHQ8VZ49, ADHL4_ARATH
Q0V7W6, ADHL5_ARATHQ8LEB2, ADHL6_ARATHQ9FH04, ADHL7_ARATH
P81601, ADHL_GADMOP39451, ADHP_ECOLIO46649, ADHP_RABIT
O46650, ADHQ_RABITQ96533, ADHX_ARATHQ3ZC42, ADHX_BOVIN
Q17335, ADHX_CAEELQ54TC2, ADHX_DICDIP46415, ADHX_DROME
P19854, ADHX_HORSEP11766, ADHX_HUMANP93629, ADHX_MAIZE
P28474, ADHX_MOUSEP80360, ADHX_MYXGLP81431, ADHX_OCTVU
A2XAZ3, ADHX_ORYSIQ0DWH1, ADHX_ORYSJP80572, ADHX_PEA
O19053, ADHX_RABITP12711, ADHX_RATP80467, ADHX_SAAHA
P86884, ADHX_SCYCAP79896, ADHX_SPAAUQ9NAR7, ADH_BACOL
P14940, ADH_CUPNEQ0KDL6, ADH_CUPNHQ00669, ADH_DROAD
P21518, ADH_DROAFP25139, ADH_DROAMQ50L96, ADH_DROAN
P48584, ADH_DROBOP22245, ADH_DRODIQ9NG42, ADH_DROEQ
P28483, ADH_DROERP48585, ADH_DROFLP51551, ADH_DROGR
Q09009, ADH_DROGUP51549, ADH_DROHAP21898, ADH_DROHE
Q07588, ADH_DROIMQ9NG40, ADH_DROINQ27404, ADH_DROLA
P10807, ADH_DROLEP07162, ADH_DROMAQ09010, ADH_DROMD
P00334, ADH_DROMEQ00671, ADH_DROMMP25721, ADH_DROMY
Q00672, ADH_DRONIP07159, ADH_DROORP84328, ADH_DROPB
P37473, ADH_DROPEP23361, ADH_DROPIP23277, ADH_DROPL
Q6LCE4, ADH_DROPSQ9U8S9, ADH_DROPUQ9GN94, ADH_DROSE
Q24641, ADH_DROSIP23278, ADH_DROSLQ03384, ADH_DROSU
P28484, ADH_DROTEP51550, ADH_DROTSB4M8Y0, ADH_DROVI
Q05114, ADH_DROWIP26719, ADH_DROYAP17648, ADH_FRAAN
P48977, ADH_MALDOQ8GIX7, ADH_MORSEP9WQC2, ADH_MYCTO
P9WQC3, ADH_MYCTUP39462, ADH_SACS2P25988, ADH_SCAAL
Q00670, ADH_SCACAP00332, ADH_SCHPOQ2FJ31, ADH_STAA3
Q2G0G1, ADH_STAA8Q2YSX0, ADH_STAABQ5HI63, ADH_STAAC
Q99W07, ADH_STAAMQ7A742, ADH_STAANQ6GJ63, ADH_STAAR
Q6GBM4, ADH_STAASQ8NXU1, ADH_STAAWQ5HRD6, ADH_STAEQ
Q8CQ56, ADH_STAESQ4J781, ADH_SULACP50381, ADH_SULSR
Q96XE0, ADH_SULTOA0A0S1X9S7, ADH_THEBAP51552, ADH_ZAPTU
Q5AR48, ASQE_EMENIA5JYX5, DHS3_CAEELP76553, EUTG_ECOLI
P41795, EUTG_SALTYP78870, FADH1_SCHPOO74540, FADH2_SCHPO
P0CL53, FADH_ASPORQ06099, FADH_CANMAP47734, FADH_METMR
P45382, FADH_PARDEO74685, FADH_PICPAP32771, FADH_YEAST
A7ZIA4, FRMA_ECO24Q8X5J4, FRMA_ECO57A7ZX04, FRMA_ECOHS
A1A835, FRMA_ECOK1Q0TKS7, FRMA_ECOL5Q8FKG1, FRMA_ECOL6
B1J085, FRMA_ECOLCP25437, FRMA_ECOLIB1LIP1, FRMA_ECOSM
Q1RFI7, FRMA_ECOUTP44557, FRMA_HAEINP39450, FRMA_PHODP
Q3Z550, FRMA_SHISSP73138, FRMA_SYNY3E1ACQ9, NOTN_ASPSM
N4WE73, OXI1_COCH4N4WE43, RED2_COCH4N4WW42, RED3_COCH4
P33010, TERPD_PSESPO07737, Y1895_MYCTU

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-