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ENZYME entry: EC 1.1.1.104

Accepted Name
4-oxoproline reductase.
Alternative Name(s)
cis-hydroxy-L-proline oxidase.
Reaction catalysed
cis-4-hydroxy-L-proline + NAD(+) <=> 4-oxo-L-proline + H(+) + NADH
Comment(s)
  • The enzyme, isolated from animals, is specific for 4-oxo-L-proline and cis-4-hydroxy-L-proline.
  • It has no activity with trans-4-hydroxy-L-proline.
Cross-references
BRENDA1.1.1.104
EC2PDB1.1.1.104
ExplorEnz1.1.1.104
PRIAM enzyme-specific profiles1.1.1.104
KEGG Ligand Database for Enzyme Nomenclature1.1.1.104
IUBMB Enzyme Nomenclature1.1.1.104
IntEnz1.1.1.104
MEDLINEFind literature relating to 1.1.1.104
MetaCyc1.1.1.104
Rhea expert-curated reactions1.1.1.104
UniProtKB/Swiss-Prot
Q3T046, DHRS6_BOVIN;  Q561X9, DHRS6_DANRE;  Q9BUT1, DHRS6_HUMAN;  
C1C4R8, DHRS6_LITCT;  Q8JZV9, DHRS6_MOUSE;  D4A1J4, DHRS6_RAT;  
Q3KPT7, DHRS6_XENLA;  

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