ID 1.1.1.110 DE aromatic 2-oxoacid reductase. AN (R)-4-hydroxyphenyllactate dehydrogenase. AN (R)-aromatic lactate dehydrogenase. AN indole-3-lactate dehydrogenase. AN indolelactate dehydrogenase. CA (1) (R)-3-phenyllactate + NAD(+) = 3-phenylpyruvate + NADH + H(+). CA (2) (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(+) = CA 3-(4-hydroxyphenyl)pyruvate + NADH + H(+). CA (3) 3-(indol-3-yl)lactate + NAD(+) = indole-3-pyruvate + NADH + H(+). CC -!- The enzymes from anaerobic bacteria such as Clostridium sporogenes CC participate in the fermentation pathways of L-phenylalanine, CC L-tyrosine and L-tryptophan. CC -!- The enzyme from the yeast Candida maltosa has similar activity, but, CC unlike the bacterial enzyme, requires Mn(2+) and can also use NADPH CC with lower activity. CC -!- Formerly EC 1.1.1.222. DR J7SHB8, FLDH_CLOS1 ; G9EZR6, FLDH_CLOS3 ; //