ID   1.1.1.110
DE   aromatic 2-oxoacid reductase.
AN   (R)-4-hydroxyphenyllactate dehydrogenase.
AN   (R)-aromatic lactate dehydrogenase.
AN   indole-3-lactate dehydrogenase.
AN   indolelactate dehydrogenase.
CA   (1) (R)-3-phenyllactate + NAD(+) = 3-phenylpyruvate + H(+) + NADH.
CA   (2) (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(+) =
CA   3-(4-hydroxyphenyl)pyruvate + H(+) + NADH.
CA   (3) 3-(indol-3-yl)lactate + NAD(+) = H(+) + indole-3-pyruvate + NADH.
CC   -!- The enzymes from anaerobic bacteria such as Clostridium sporogenes
CC       participate in the fermentation pathways of L-phenylalanine,
CC       L-tyrosine and L-tryptophan.
CC   -!- The enzyme from the yeast Candida maltosa has similar activity, but,
CC       unlike the bacterial enzyme, requires Mn(2+) and can also use NADPH
CC       with lower activity.
CC   -!- Formerly EC 1.1.1.222.
DR   J7SHB8, FLDH_CLOS1 ;  G9EZR6, FLDH_CLOS3 ;
//