ENZYME entry: EC 1.1.1.127

Accepted Name

2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase.

Alternative Name(s)

2-keto-3-deoxygluconate dehydrogenase.

Reaction catalysed

2-dehydro-3-deoxy-D-gluconate + NAD(+) <=> (4S)-4,6-dihydroxy-2,5-dioxohexanoate + NADH

Comment(s)

The enzyme from Pseudomonas acts equally well on NAD(+) or NADP(+), while those from Erwinia chrysanthemi and Escherichia coli are more specific for NAD(+).

Cross-references

BRENDA

1.1.1.127

EC2PDB

1.1.1.127

ExplorEnz

1.1.1.127

PRIAM enzyme-specific profiles

1.1.1.127

KEGG Ligand Database for Enzyme Nomenclature

1.1.1.127

IUBMB Enzyme Nomenclature

1.1.1.127

IntEnz

1.1.1.127

MEDLINE

Find literature relating to 1.1.1.127

MetaCyc

1.1.1.127

UniProtKB/Swiss-Prot

P50842, KDUD_BACSU;	Q05528, KDUD_DICD3;	P37769, KDUD_ECOLI;
T2KLZ8, PLH6_FORAG;

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