ENZYME entry: EC 1.1.1.136
| Accepted Name |
|---|
| UDP-N-acetylglucosamine 6-dehydrogenase.
|
| Alternative Name(s) |
|---|
| UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase. |
| Reaction catalysed |
|---|
| H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine <=> 3 H(+) + 2 NADH + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate |
| Comment(s) |
|---|
| This enzyme participates in the biosynthetic pathway for UDP-alpha-D-
ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic
acid), an important precursor of B-band lipopolysaccharide.
|
| Cross-references |
|---|
| BRENDA | 1.1.1.136 |
| EC2PDB | 1.1.1.136 |
| ExplorEnz | 1.1.1.136 |
| PRIAM enzyme-specific profiles | 1.1.1.136 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.136 |
| IUBMB Enzyme Nomenclature | 1.1.1.136 |
| IntEnz | 1.1.1.136 |
| MEDLINE | Find literature relating to 1.1.1.136 |
| MetaCyc | 1.1.1.136 |
| Rhea expert-curated reactions | 1.1.1.136 |
| UniProtKB/Swiss-Prot |
|
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