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ENZYME

ENZYME entry: EC 1.1.1.14

PURL: https://purl.expasy.org/enzyme/EC/1.1.1.14
Accepted Name
L-iditol 2-dehydrogenase
Alternative Name(s)
glucitol dehydrogenase
polyol dehydrogenase
sorbitol dehydrogenase
Reaction catalysed
L-iditol + NAD(+) = keto-L-sorbose + NADH + H(+)
Comment(s)
  • This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.
  • It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.
  • Enzymes from different organisms or tissues display different substrate specificity.
  • The enzyme is specific to NAD(+) and can not use NADP(+).
Cross-references
BRENDA1.1.1.14
EC2PDB1.1.1.14
ExplorEnz1.1.1.14
KEGG Ligand Database for Enzyme Nomenclature1.1.1.14
IUBMB Enzyme Nomenclature1.1.1.14
MEDLINEFind literature relating to 1.1.1.14
MetaCyc1.1.1.14
Rhea expert-curated reactions1.1.1.14
UniProtKB/Swiss-Prot
Q06004, DHSO_BACSUQ02912, DHSO_BOMMOQ58D31, DHSO_BOVIN
Q9Z9U1, DHSO_HALH5Q00796, DHSO_HUMANQ4R639, DHSO_MACFA
Q64442, DHSO_MOUSEQ29318, DHSO_PIGQ5R5F3, DHSO_PONAB
P27867, DHSO_RATP07846, DHSO_SHEEPQ59787, SDH_CERSP

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
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