ENZYME entry: EC 1.1.1.141
Accepted Name |
15-hydroxyprostaglandin dehydrogenase (NAD(+)).
|
Alternative Name(s) |
15-hydroxyprostaglandin dehydrogenase. |
Reaction catalysed |
(5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoate + NAD(+) <=> (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + NADH |
Comment(s) |
Acts on prostaglandins E(2), F(2-alpha) and B(1), but not on
prostaglandin D(2) (cf. EC 1.1.1.196 and EC 1.1.1.197).
|
Cross-references |
PROSITE | PDOC00060 |
BRENDA | 1.1.1.141 |
EC2PDB | 1.1.1.141 |
ExplorEnz | 1.1.1.141 |
PRIAM enzyme-specific profiles | 1.1.1.141 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.141 |
IUBMB Enzyme Nomenclature | 1.1.1.141 |
IntEnz | 1.1.1.141 |
MEDLINE | Find literature relating to 1.1.1.141 |
MetaCyc | 1.1.1.141 |
UniProtKB/Swiss-Prot |
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