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ENZYME entry: EC 1.1.1.181

Accepted Name
cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase.
Alternative Name(s)
3beta-hydroxy-Delta(5)-C27-steroid oxidoreductase.
Reaction catalysed
7alpha-hydroxycholesterol + NAD(+) <=> 7alpha-hydroxycholest-4-en-3-one + H(+) + NADH
Comment(s)
Highly specific for 3beta-hydroxy-C27-steroids with Delta(5)-double bond.
Cross-references
BRENDA1.1.1.181
EC2PDB1.1.1.181
ExplorEnz1.1.1.181
PRIAM enzyme-specific profiles1.1.1.181
KEGG Ligand Database for Enzyme Nomenclature1.1.1.181
IUBMB Enzyme Nomenclature1.1.1.181
IntEnz1.1.1.181
MEDLINEFind literature relating to 1.1.1.181
MetaCyc1.1.1.181
Rhea expert-curated reactions1.1.1.181
UniProtKB/Swiss-Prot
Q9H2F3, 3BHS7_HUMAN;  Q9EQC1, 3BHS7_MOUSE;  O35048, 3BHS7_RAT;  

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