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ENZYME

ENZYME entry: EC 1.1.1.187

PURL: https://purl.expasy.org/enzyme/EC/1.1.1.187
Accepted Name
GDP-4-dehydro-D-rhamnose reductase
Alternative Name(s)
GDP-4-keto-6-deoxy-D-mannose reductase
GDP-4-keto-D-rhamnose reductase
guanosine diphosphate-4-keto-D-rhamnose reductase
Reaction catalysed
  • GDP-alpha-D-rhamnose + NAD(+) = GDP-4-dehydro-alpha-D-rhamnose + NADH + H(+)
  • GDP-alpha-D-rhamnose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH + H(+)
  • GDP-6-deoxy-alpha-D-talose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH + H(+)
  • GDP-6-deoxy-alpha-D-talose + NAD(+) = GDP-4-dehydro-alpha-D-rhamnose + NADH + H(+)
Comment(s)
The enzyme, which operates in the opposite direction to that shown, forms a mixture of GDP-alpha-D-rhamnose and its C-4 epimer, GDP-6- deoxy-alpha-D-talose. cf. EC 1.1.1.135 and EC 1.1.1.281.
Cross-references
BRENDA1.1.1.187
EC2PDB1.1.1.187
ExplorEnz1.1.1.187
KEGG Ligand Database for Enzyme Nomenclature1.1.1.187
IUBMB Enzyme Nomenclature1.1.1.187
MEDLINEFind literature relating to 1.1.1.187
MetaCyc1.1.1.187
Rhea expert-curated reactions1.1.1.187

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-