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ENZYME entry: EC 1.1.1.188
Accepted Name |
prostaglandin-F synthase.
|
Alternative Name(s) |
PGD2 11-ketoreductase. |
PGF synthetase. |
prostaglandin 11-ketoreductase. |
prostaglandin-D2 11-ketoreductase. |
prostaglandin-D2 11-reductase. |
prostaglandin-D2 ketoreductase. |
prostaglandin-F synthetase. |
Reaction catalysed |
NADP(+) + prostaglandin F2alpha <=> H(+) + NADPH + prostaglandin D2 |
Comment(s) |
- Reduces prostaglandin D2 and prostaglandin H2 to prostaglandin F2;
prostaglandin D2 is not an intermediate in the reduction of
prostaglandin H2.
- Also catalyzes the reduction of a number of carbonyl compounds, such
as 9,10-phenanthroquinone and 4-nitroacetophenone.
|
Cross-references |
BRENDA | 1.1.1.188 |
EC2PDB | 1.1.1.188 |
ExplorEnz | 1.1.1.188 |
PRIAM enzyme-specific profiles | 1.1.1.188 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.188 |
IUBMB Enzyme Nomenclature | 1.1.1.188 |
IntEnz | 1.1.1.188 |
MEDLINE | Find literature relating to 1.1.1.188 |
MetaCyc | 1.1.1.188 |
Rhea expert-curated reactions | 1.1.1.188 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
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