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ENZYME

ENZYME entry: EC 1.1.1.189

Accepted Name
prostaglandin-E2 9-reductase
Alternative Name(s)
9-keto-prostaglandin E2 reductase
9-ketoprostaglandin reductase
PGE2 9-ketoreductase
PGE2 9-oxoreductase
prostaglandin-E2 9-oxoreductase
Reaction catalysed
NADP(+) + prostaglandin F2alpha <=> H(+) + NADPH + prostaglandin E2
Comment(s)
  • Reduces prostaglandin E2 to prostaglandin F2alpha.
  • A number of other 9-oxo- and 15-oxo-prostaglandin derivatives can also be reduced to the corresponding hydroxy compounds.
  • May be identical with EC 1.1.1.197.
Cross-references
BRENDA1.1.1.189
EC2PDB1.1.1.189
ExplorEnz1.1.1.189
PRIAM enzyme-specific profiles1.1.1.189
KEGG Ligand Database for Enzyme Nomenclature1.1.1.189
IUBMB Enzyme Nomenclature1.1.1.189
IntEnz1.1.1.189
MEDLINEFind literature relating to 1.1.1.189
MetaCyc1.1.1.189
Rhea expert-curated reactions1.1.1.189
UniProtKB/Swiss-Prot
Q3SZD7, CBR1_BOVINP16152, CBR1_HUMANQ8MI29, CBR1_MACFA
P48758, CBR1_MOUSEQ28960, CBR1_PIGQ5RCU5, CBR1_PONAB
P47844, CBR1_RABITP47727, CBR1_RATP80508, PE2R_RABIT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
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