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ENZYME entry: EC 1.1.1.2

Accepted Name
Alcohol dehydrogenase (NADP(+)).
Alternative Name(s)
Aldehyde reductase (NADPH).
Reaction catalysed
An alcohol + NADP(+) <=> an aldehyde + NADPH
Cofactor(s)
Zn(2+).
Comment(s)
  • Some members of this group oxidize only primary alcohols; others act also on secondary alcohols.
  • May be identical with EC 1.1.1.19, EC 1.1.1.33 and EC 1.1.1.55.
  • Re-specific with respect to NADPH.
Cross-references
PROSITEPDOC00061
BRENDA1.1.1.2
EC2PDB1.1.1.2
ExplorEnz1.1.1.2
PRIAM enzyme-specific profiles1.1.1.2
KEGG Ligand Database for Enzyme Nomenclature1.1.1.2
IUBMB Enzyme Nomenclature1.1.1.2
IntEnz1.1.1.2
MEDLINEFind literature relating to 1.1.1.2
MetaCyc1.1.1.2
Rhea expert-curated reactions1.1.1.2
UniProtKB/Swiss-Prot
Q6AZW2, A1A1A_DANRE;  Q568L5, A1A1B_DANRE;  Q24857, ADH3_ENTHI;  
Q04894, ADH6_YEAST;  P25377, ADH7_YEAST;  O57380, ADH8_PELPE;  
P74721, ADHA_SYNY3;  Q9F282, ADHA_THEET;  P0CH36, ADHC1_MYCS2;  
P0CH37, ADHC2_MYCS2;  P0A4X1, ADHC_MYCBO;  P9WQC4, ADHC_MYCTO;  
P9WQC5, ADHC_MYCTU;  P27250, AHR_ECOLI;  Q3ZCJ2, AK1A1_BOVIN;  
Q5ZK84, AK1A1_CHICK;  O70473, AK1A1_CRIGR;  P14550, AK1A1_HUMAN;  
Q9JII6, AK1A1_MOUSE;  P50578, AK1A1_PIG;  Q5R5D5, AK1A1_PONAB;  
P51635, AK1A1_RAT;  Q6GMC7, AK1A1_XENLA;  Q28FD1, AK1A1_XENTR;  
Q9UUN9, ALD2_SPOSA;  P27800, ALDX_SPOSA;  P75691, YAHK_ECOLI;  

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