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ENZYME entry: EC 1.1.1.200

Accepted Name
aldose-6-phosphate reductase (NADPH).
Alternative Name(s)
NADP-dependent D-sorbitol-6-phosphate dehydrogenase.
Reaction catalysed
D-sorbitol 6-phosphate + NADP(+) <=> aldehydo-D-glucose 6-phosphate + H(+) + NADPH
Comment(s)
In the reverse reaction, acts also on D-galactose 6-phosphate and, more slowly, on D-mannose 6-phosphate and 2-deoxy-D-glucose 6-phosphate.
Cross-references
BRENDA1.1.1.200
EC2PDB1.1.1.200
ExplorEnz1.1.1.200
PRIAM enzyme-specific profiles1.1.1.200
KEGG Ligand Database for Enzyme Nomenclature1.1.1.200
IUBMB Enzyme Nomenclature1.1.1.200
IntEnz1.1.1.200
MEDLINEFind literature relating to 1.1.1.200
MetaCyc1.1.1.200
Rhea expert-curated reactions1.1.1.200
UniProtKB/Swiss-Prot
P28475, S6PD_MALDO

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