A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.1.1.203
| Accepted Name |
|---|
| Uronate dehydrogenase.
|
| Alternative Name(s) |
|---|
| Uronic acid dehydrogenase. |
| Reaction catalysed |
|---|
- Beta-D-galacturonate + NAD(+) <=> D-galactaro-1,5-lactone + NADH
- Beta-D-glucuronate + NAD(+) <=> D-glucaro-1,5-lactone + NADH
|
| Cofactor(s) |
|---|
| Mg(2+).
|
| Comment(s) |
|---|
- The enzyme, characterized from the bacterium Agrobacterium fabrum,
participates in oxidative degradation pathways for galacturonate and
glucuronate.
- The enzyme can only accept the beta anomeric form of the substrate.
- The 1,5 lactone product is rather stable at cytosolic pH and does not
hydrolyze spontaneously at a substantial rate.
- Formerly EC 1.2.1.35.
|
| Cross-references |
|---|
| BRENDA | 1.1.1.203 |
| EC2PDB | 1.1.1.203 |
| ExplorEnz | 1.1.1.203 |
| PRIAM enzyme-specific profiles | 1.1.1.203 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.203 |
| IUBMB Enzyme Nomenclature | 1.1.1.203 |
| IntEnz | 1.1.1.203 |
| MEDLINE | Find literature relating to 1.1.1.203 |
| MetaCyc | 1.1.1.203 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-