ENZYME entry: EC 1.1.1.203
Accepted Name |
uronate dehydrogenase.
|
Alternative Name(s) |
uronic acid dehydrogenase. |
Reaction catalysed |
- beta-D-galacturonate + NAD(+) <=> D-galactaro-1,5-lactone + H(+) + NADH
- beta-D-glucuronate + NAD(+) <=> D-glucaro-1,5-lactone + H(+) + NADH
|
Comment(s) |
- The enzyme, characterized from the bacterium Agrobacterium fabrum,
participates in oxidative degradation pathways for galacturonate and
glucuronate.
- The enzyme can only accept the beta anomeric form of the substrate.
- The 1,5 lactone product is rather stable at cytosolic pH and does not
hydrolyze spontaneously at a substantial rate.
- Formerly EC 1.2.1.35.
|
Cross-references |
BRENDA | 1.1.1.203 |
EC2PDB | 1.1.1.203 |
ExplorEnz | 1.1.1.203 |
PRIAM enzyme-specific profiles | 1.1.1.203 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.203 |
IUBMB Enzyme Nomenclature | 1.1.1.203 |
IntEnz | 1.1.1.203 |
MEDLINE | Find literature relating to 1.1.1.203 |
MetaCyc | 1.1.1.203 |
Rhea expert-curated reactions | 1.1.1.203 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-