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ENZYME entry: EC 1.1.1.210

Accepted Name
3beta-(or 20alpha)-hydroxysteroid dehydrogenase.
Alternative Name(s)
3-beta-HSD.
progesterone reductase.
Reaction catalysed
5alpha-androstane-3beta,17beta-diol + NADP(+) <=> 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH
Comment(s)
Also acts on 20alpha-hydroxysteroids.
Cross-references
BRENDA1.1.1.210
EC2PDB1.1.1.210
ExplorEnz1.1.1.210
PRIAM enzyme-specific profiles1.1.1.210
KEGG Ligand Database for Enzyme Nomenclature1.1.1.210
IUBMB Enzyme Nomenclature1.1.1.210
IntEnz1.1.1.210
MEDLINEFind literature relating to 1.1.1.210
MetaCyc1.1.1.210
Rhea expert-curated reactions1.1.1.210
UniProtKB/Swiss-Prot
P14060, 3BHS1_HUMAN;  P27365, 3BHS1_MACMU;  Q60555, 3BHS1_MESAU;  
P24815, 3BHS1_MOUSE;  P22071, 3BHS1_RAT;  O35296, 3BHS3_MESAU;  
Q61767, 3BHS4_MOUSE;  Q61694, 3BHS5_MOUSE;  P27364, 3BHS5_RAT;  
Q04828, AK1C1_HUMAN;  Q95JH7, AK1C1_MACFA;  Q95JH6, AK1C1_MACFU;  
Q5REQ0, AK1C1_PONAB;  P42330, AK1C3_HUMAN;  Q5R7C9, AK1C3_PONAB;  
P17516, AK1C4_HUMAN;  Q95JH5, AK1C4_MACFA;  Q95JH4, AK1C4_MACFU;  
P56937, DHB7_HUMAN;  O88736, DHB7_MOUSE;  Q62904, DHB7_RAT;  

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