ENZYME entry: EC 1.1.1.219
| Accepted Name |
|---|
| Dihydroflavanol 4-reductase.
|
| Alternative Name(s) |
|---|
| Dihydroflavonol 4-reductase. |
| Dihydrokaempferol 4-reductase. |
| NADPH-dihydromyricetin reductase. |
| Reaction catalysed |
|---|
| A (2R,3S,4S)-leucoanthocyanidin + NADP(+) <=> a (2R,3R)-dihydroflavonol + NADPH |
| Comment(s) |
|---|
- This plant enzyme, involved in the biosynthesis of anthocyanidins,
is known to act on (+)-dihydrokaempferol, (+)-taxifolin, and (+)-
dihydromyricetin, although some enzymes may act only on a subset of
these compounds.
- Each dihydroflavonol is reduced to the corresponding cis-flavan-3,4-
diol.
- NAD(+) can act instead of NADP(+), but more slowly.
|
| Cross-references |
|---|
| BRENDA | 1.1.1.219 |
| EC2PDB | 1.1.1.219 |
| ExplorEnz | 1.1.1.219 |
| PRIAM enzyme-specific profiles | 1.1.1.219 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.219 |
| IUBMB Enzyme Nomenclature | 1.1.1.219 |
| IntEnz | 1.1.1.219 |
| MEDLINE | Find literature relating to 1.1.1.219 |
| MetaCyc | 1.1.1.219 |
| UniProtKB/Swiss-Prot |
| P14721, DFRA_ANTMA; | P51102, DFRA_ARATH; | P51103, DFRA_CALCH; |
| P51104, DFRA_DIACA; | P51105, DFRA_GERHY; | P51106, DFRA_HORVU; |
| P51108, DFRA_MAIZE; | Q9XES5, DFRA_MALDO; | P51109, DFRA_MEDSA; |
| P14720, DFRA_PETHY; | Q84KP0, DFRA_PYRCO; | P51107, DFRA_SOLLC; |
| P73212, DFRA_SYNY3; | P51110, DFRA_VITVI; |
|
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