ENZYME entry: EC 1.1.1.219
Accepted Name |
Dihydroflavanol 4-reductase.
|
Alternative Name(s) |
Dihydroflavonol 4-reductase. |
Dihydrokaempferol 4-reductase. |
NADPH-dihydromyricetin reductase. |
Reaction catalysed |
A (2R,3S,4S)-leucoanthocyanidin + NADP(+) <=> a (2R,3R)-dihydroflavonol + NADPH |
Comment(s) |
- This plant enzyme, involved in the biosynthesis of anthocyanidins,
is known to act on (+)-dihydrokaempferol, (+)-taxifolin, and (+)-
dihydromyricetin, although some enzymes may act only on a subset of
these compounds.
- Each dihydroflavonol is reduced to the corresponding cis-flavan-3,4-
diol.
- NAD(+) can act instead of NADP(+), but more slowly.
|
Cross-references |
BRENDA | 1.1.1.219 |
EC2PDB | 1.1.1.219 |
ExplorEnz | 1.1.1.219 |
PRIAM enzyme-specific profiles | 1.1.1.219 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.219 |
IUBMB Enzyme Nomenclature | 1.1.1.219 |
IntEnz | 1.1.1.219 |
MEDLINE | Find literature relating to 1.1.1.219 |
MetaCyc | 1.1.1.219 |
Rhea expert-curated reactions | 1.1.1.219 |
UniProtKB/Swiss-Prot |
P14721, DFRA_ANTMA; | P51102, DFRA_ARATH; | P51103, DFRA_CALCH; |
P51104, DFRA_DIACA; | P51105, DFRA_GERHY; | P51106, DFRA_HORVU; |
P51108, DFRA_MAIZE; | Q9XES5, DFRA_MALDO; | P51109, DFRA_MEDSA; |
P14720, DFRA_PETHY; | Q84KP0, DFRA_PYRCO; | P51107, DFRA_SOLLC; |
P73212, DFRA_SYNY3; | P51110, DFRA_VITVI; |
|
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