ID 1.1.1.224 DE mannose-6-phosphate 6-reductase. AN NADPH-dependent M6P reductase. AN NADPH-mannose-6-P reductase. CA D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + H(+) + NADPH. CC -!- Involved in the biosynthesis of mannitol in celery (Apium graveolens) CC leaves. //