ID 1.1.1.226 DE trans-4-hydroxycyclohexanecarboxylate dehydrogenase. AN 4-hydroxycyclohexanecarboxylate dehydrogenase. CA NAD(+) + trans-4-hydroxycyclohexane-1-carboxylate = 4-oxocyclohexane-1- CA carboxylate + H(+) + NADH. CC -!- The enzyme from Corynebacterium cyclohexanicum is highly specific for CC the trans-4-hydroxy derivative. cf. cis-4- CC hydroxycyclohexanecarboxylate dehydrogenase. //