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ENZYME entry: EC 1.1.1.237

Accepted Name
Hydroxyphenylpyruvate reductase.
Reaction catalysed
  • (R)-3-(4-hydroxyphenyl)lactate + NAD(P)(+) <=> 3-(4-hydroxyphenyl)pyruvate + NAD(P)H
  • (R)-3-(3,4-dihydroxyphenyl)lactate + NAD(P)(+) <=> 3-(3,4-dihydroxyphenyl)pyruvate + NAD(P)H
Comment(s)
  • The enzyme participates in the biosynthesis of rosmarinic acid.
  • It belongs to the family of D-isomer-specific 2-hydroxyacid dehydrogenases, and prefers NADPH to NADH.
Cross-references
BRENDA1.1.1.237
EC2PDB1.1.1.237
ExplorEnz1.1.1.237
PRIAM enzyme-specific profiles1.1.1.237
KEGG Ligand Database for Enzyme Nomenclature1.1.1.237
IUBMB Enzyme Nomenclature1.1.1.237
IntEnz1.1.1.237
MEDLINEFind literature relating to 1.1.1.237
MetaCyc1.1.1.237
UniProtKB/Swiss-Prot
P58409, HCXB_ECO57;  P30178, HCXB_ECOLI;  Q65CJ7, HPPR_PLESU;  

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