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ENZYME entry: EC 1.1.1.238

Accepted Name
12beta-hydroxysteroid dehydrogenase.
Reaction catalysed
3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+) <=> 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH
Comment(s)
Acts on a number of bile acids, both in their free and conjugated forms.
Cross-references
BRENDA1.1.1.238
EC2PDB1.1.1.238
ExplorEnz1.1.1.238
PRIAM enzyme-specific profiles1.1.1.238
KEGG Ligand Database for Enzyme Nomenclature1.1.1.238
IUBMB Enzyme Nomenclature1.1.1.238
IntEnz1.1.1.238
MEDLINEFind literature relating to 1.1.1.238
MetaCyc1.1.1.238
Rhea expert-curated reactions1.1.1.238

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-