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ENZYME

ENZYME entry: EC 1.1.1.252

PURL: https://purl.expasy.org/enzyme/EC/1.1.1.252
Accepted Name
tetrahydroxynaphthalene reductase
Alternative Name(s)
T4HN reductase
Reaction catalysed
scytalone + NADP(+) = naphthalene-1,3,6,8-tetrol + NADPH + H(+)
Comment(s)
  • Reduces 1,3,6,8-tetrahydroxynaphthalene to scytalone and also reduces 1,3,8-trihydroxynaphthalene to vermelone.
  • Involved with EC 4.2.1.94 in the biosynthesis of melanin in pathogenic fungi.
  • Formerly EC 1.3.1.50.
Cross-references
BRENDA1.1.1.252
EC2PDB1.1.1.252
ExplorEnz1.1.1.252
KEGG Ligand Database for Enzyme Nomenclature1.1.1.252
IUBMB Enzyme Nomenclature1.1.1.252
MEDLINEFind literature relating to 1.1.1.252
MetaCyc1.1.1.252
Rhea expert-curated reactions1.1.1.252
UniProtKB/Swiss-Prot
W3XAA0, PFMAG_PESFWQ12634, T4HR_PYRO7F9XMW6, T4HR_ZYMTI

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