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ENZYME entry: EC 1.1.1.255

Accepted Name
Mannitol dehydrogenase.
Alternative Name(s)
MTD.
NAD-dependent mannitol dehydrogenase.
Reaction catalysed
D-mannitol + NAD(+) <=> D-mannose + NADH
Comment(s)
  • The enzyme from Apium graveolens (celery) oxidizes alditols with a minimum requirement of 2R chirality at the carbon adjacent to the primary carbon undergoing the oxidation.
  • The enzyme is specific for NAD(+) and does not use NADP(+).
Cross-references
BRENDA1.1.1.255
EC2PDB1.1.1.255
ExplorEnz1.1.1.255
PRIAM enzyme-specific profiles1.1.1.255
KEGG Ligand Database for Enzyme Nomenclature1.1.1.255
IUBMB Enzyme Nomenclature1.1.1.255
IntEnz1.1.1.255
MEDLINEFind literature relating to 1.1.1.255
MetaCyc1.1.1.255
Rhea expert-curated reactions1.1.1.255
UniProtKB/Swiss-Prot
Q43137, MTDH1_STYHU;  Q43138, MTDH3_STYHU;  Q38707, MTDH_APIGR;  
Q9ZRF1, MTDH_FRAAN;  O82515, MTDH_MEDSA;  P93257, MTDH_MESCR;  
P42754, MTDH_PETCR;  

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