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ENZYME entry: EC 1.1.1.263

Accepted Name
1,5-anhydro-D-fructose reductase.
Alternative Name(s)
AF reductase.
Reaction catalysed
1,5-anhydro-D-glucitol + NADP(+) <=> 1,5-anhydro-D-fructose + H(+) + NADPH
Comment(s)
  • Also reduces pyridine-3-aldehyde and 2,3-butanedione.
  • Acetaldehyde, 2-dehydroglucose (glucosone) and glucuronate are poor substrates, but there is no detectable action on glucose, mannose and fructose.
Cross-references
BRENDA1.1.1.263
EC2PDB1.1.1.263
ExplorEnz1.1.1.263
PRIAM enzyme-specific profiles1.1.1.263
KEGG Ligand Database for Enzyme Nomenclature1.1.1.263
IUBMB Enzyme Nomenclature1.1.1.263
IntEnz1.1.1.263
MEDLINEFind literature relating to 1.1.1.263
MetaCyc1.1.1.263
Rhea expert-curated reactions1.1.1.263
UniProtKB/Swiss-Prot
Q96JD6, AKCL2_HUMAN;  Q4R802, AKCL2_MACFA;  Q9DCT1, AKCL2_MOUSE;  
P82125, AKCL2_PIG;  Q5U1Y4, AKCL2_RAT;  

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