ID   1.1.1.266
DE   dTDP-4-dehydro-6-deoxyglucose reductase.
AN   dTDP-4-keto-6-deoxyglucose reductase.
CA   (1) dTDP-alpha-D-fucose + NAD(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose
CA   + H(+) + NADH.
CA   (2) dTDP-alpha-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-
CA   glucose + H(+) + NADPH.
CC   -!- The enzymes from the Gram-negative bacteria Actinobacillus
CC       actinomycetemcomitans and Escherichia coli O52 are involved in
CC       activation of fucose for incorporation into capsular polysaccharide
CC       O-antigens.
CC   -!- The enzyme from the Gram-positive bacterium Anoxybacillus tepidamans
CC       (Geobacillus tepidamans) is involved in activation of fucose for
CC       incorporation into the organism's S-layer.
CC   -!- The enzyme from E. coli O52 has a higher catalytic efficiency with
CC       NADH than with NADPH.
DR   Q6E7F2, FCF1_ECOLX ;
//