ID   1.1.1.270
DE   3beta-hydroxysteroid 3-dehydrogenase.
AN   3-keto-steroid reductase.
AN   3-KSR.
CA   a 3beta-hydroxysteroid + NADP(+) = a 3-oxosteroid + H(+) + NADPH.
CC   -!- The enzyme acts on multiple 3beta-hydroxysteroids.
CC   -!- Participates in the biosynthesis of zemosterol and cholesterol, where
CC       it catalyzes the reaction in the opposite direction to that shown.
CC   -!- The mammalian enzyme is bifunctional and also catalyzes EC 1.1.1.62.
DR   P14060, 3BHS1_HUMAN;  P27365, 3BHS1_MACMU;  Q60555, 3BHS1_MESAU;
DR   P24815, 3BHS1_MOUSE;  P22071, 3BHS1_RAT  ;  O35296, 3BHS3_MESAU;
DR   Q61767, 3BHS4_MOUSE;  Q61694, 3BHS5_MOUSE;  P27364, 3BHS5_RAT  ;
DR   P56937, DHB7_HUMAN ;  O88736, DHB7_MOUSE ;  Q62904, DHB7_RAT   ;
DR   Q3ZBV9, DHR11_BOVIN;  Q71R50, DHR11_CHICK;  Q6UWP2, DHR11_HUMAN;
DR   Q3U0B3, DHR11_MOUSE;  Q5A888, ERG27_CANAL;  Q874K0, ERG27_CANAX;
DR   Q6FIV3, ERG27_CANGA;  Q6BNP0, ERG27_DEBHA;  Q74ZZ0, ERG27_EREGS;
DR   Q6CJC2, ERG27_KLULA;  O74732, ERG27_SCHPO;  Q6CE88, ERG27_YARLI;
DR   Q12452, ERG27_YEAST;  Q60A54, SDMB_METCA ;
//