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ENZYME entry: EC 1.1.1.271

Accepted Name
GDP-L-fucose synthase.
Alternative Name(s)
GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase.
GDP-fucose synthetase.
Reaction catalysed
GDP-beta-L-fucose + NADP(+) <=> GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH
Comment(s)
Both human and Escherichia coli enzymes can use NADH in place of NADPH to a slight extent.
Cross-references
BRENDA1.1.1.271
EC2PDB1.1.1.271
ExplorEnz1.1.1.271
PRIAM enzyme-specific profiles1.1.1.271
KEGG Ligand Database for Enzyme Nomenclature1.1.1.271
IUBMB Enzyme Nomenclature1.1.1.271
IntEnz1.1.1.271
MEDLINEFind literature relating to 1.1.1.271
MetaCyc1.1.1.271
Rhea expert-curated reactions1.1.1.271
UniProtKB/Swiss-Prot
O49213, FCL1_ARATH;  Q67WR2, FCL1_ORYSJ;  Q9LMU0, FCL2_ARATH;  
Q67WR5, FCL2_ORYSJ;  P33217, FCL_AZOC5;  G5EER4, FCL_CAEEL;  
Q8K3X2, FCL_CRIGR;  Q55C77, FCL_DICDI;  Q9W1X8, FCL_DROME;  
P32055, FCL_ECOLI;  Q13630, FCL_HUMAN;  P23591, FCL_MOUSE;  
Q5RBE5, FCL_PONAB;  P55353, FCL_SINFN;  

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