ID   1.1.1.282
DE   quinate/shikimate dehydrogenase [NAD(P)(+)].
AN   quinate/shikimate dehydrogenase.
CA   (1) L-quinate + NADP(+) = 3-dehydroquinate + H(+) + NADPH.
CA   (2) L-quinate + NAD(+) = 3-dehydroquinate + H(+) + NADH.
CA   (3) NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH.
CA   (4) NAD(+) + shikimate = 3-dehydroshikimate + H(+) + NADH.
CC   -!- This is the second shikimate dehydrogenase enzyme found in
CC       Escherichia coli.
CC   -!- It can use both quinate and shikimate as substrates and either NAD(+)
CC       or NADP(+) as acceptor.
CC   -!- The low catalytic efficiency with both quinate and shikimate suggests
CC       that neither may be the physiological substrate. cf. EC 1.1.1.24,
CC       EC 1.1.1.25, and EC 1.1.5.8.
DR   A7ZMF7, YDIB_ECO24 ;  B7US31, YDIB_ECO27 ;  B7MAQ2, YDIB_ECO45 ;
DR   B7L5P4, YDIB_ECO55 ;  Q8X5Y4, YDIB_ECO57 ;  B5YPX9, YDIB_ECO5E ;
DR   B7NTU4, YDIB_ECO7I ;  B7MVG8, YDIB_ECO81 ;  B7M0P8, YDIB_ECO8A ;
DR   C4ZYF4, YDIB_ECOBW ;  B1XG00, YDIB_ECODH ;  A8A0N8, YDIB_ECOHS ;
DR   A1ABM9, YDIB_ECOK1 ;  Q0THD7, YDIB_ECOL5 ;  P0A6D6, YDIB_ECOL6 ;
DR   B1IQ64, YDIB_ECOLC ;  P0A6D5, YDIB_ECOLI ;  B7N528, YDIB_ECOLU ;
DR   B6IBD2, YDIB_ECOSE ;  B1LE44, YDIB_ECOSM ;  Q1RBA4, YDIB_ECOUT ;
DR   B5F7D6, YDIB_SALA4 ;  Q57PS7, YDIB_SALCH ;  B5FJ81, YDIB_SALDC ;
DR   B5QVU2, YDIB_SALEP ;  B5RAU7, YDIB_SALG2 ;  B4TGJ7, YDIB_SALHS ;
DR   B4T4Q4, YDIB_SALNS ;  A9N158, YDIB_SALPB ;  B4TUS3, YDIB_SALSV ;
DR   Q8ZPR4, YDIB_SALTY ;  B2U2J6, YDIB_SHIB3 ;  P0C2L9, YDIB_SHIBS ;
DR   Q32GE1, YDIB_SHIDS ;  Q0T479, YDIB_SHIF8 ;  Q83RA2, YDIB_SHIFL ;
DR   Q3Z246, YDIB_SHISS ;
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