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ENZYME entry: EC 1.1.1.302
| Accepted Name |
|---|
| 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase.
|
| Alternative Name(s) |
|---|
| 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase. |
| Reaction catalysed |
|---|
- 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) <=> 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADH
- 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) <=> 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADPH
|
| Comment(s) |
|---|
- The reaction proceeds in the opposite direction.
- A step in riboflavin biosynthesis, NADPH and NADH function equally
well as reductant.
- Differs from EC 1.1.1.193 since it does not catalyze the reduction of
5-amino-6-ribosylaminopyrimidine-2,4(1H,3H)-dione 5'-phosphate.
|
| Cross-references |
|---|
| BRENDA | 1.1.1.302 |
| EC2PDB | 1.1.1.302 |
| ExplorEnz | 1.1.1.302 |
| PRIAM enzyme-specific profiles | 1.1.1.302 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.302 |
| IUBMB Enzyme Nomenclature | 1.1.1.302 |
| IntEnz | 1.1.1.302 |
| MEDLINE | Find literature relating to 1.1.1.302 |
| MetaCyc | 1.1.1.302 |
| Rhea expert-curated reactions | 1.1.1.302 |
| UniProtKB/Swiss-Prot |
| O66747, RIB7_AQUAE; | O28272, RIB7_ARCFU; | Q757H6, RIB7_ASHGO; |
| Q6FU96, RIB7_CANGA; | Q6BII9, RIB7_DEBHA; | Q6CJ61, RIB7_KLULA; |
| Q9P4B8, RIB7_KLUMA; | Q58085, RIB7_METJA; | O26337, RIB7_METTH; |
| P95872, RIB7_SACS2; | Q9P7L3, RIB7_SCHPO; | P33312, RIB7_YEAST; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
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