ID   1.1.1.307
DE   D-xylose reductase [NAD(P)H].
AN   D-xylose reductase.
AN   xylose reductase.
CA   (1) NAD(+) + xylitol = D-xylose + H(+) + NADH.
CA   (2) NADP(+) + xylitol = D-xylose + H(+) + NADPH.
CC   -!- Xylose reductases catalyze the reduction of xylose to xylitol,
CC       the initial reaction in the fungal D-xylose degradation pathway.
CC   -!- Most of the enzymes exhibit a strict requirement for NADPH (cf.
CC       EC 1.1.1.431).
CC   -!- However, a few D-xylose reductases, such as those from Neurospora
CC       crassa, Yamadazyma tenuis, Scheffersomyces stipitis, and the
CC       thermophilic fungus Chaetomium thermophilum, have dual cofactor
CC       specificity, though they still prefer NADPH to NADH.
CC   -!- Very rarely the enzyme prefers NADH (cf. EC 1.1.1.430).
DR   C5FFQ7, XYL1_ARTOC ;  A1CRI1, XYL1_ASPCL ;  B0XNR0, XYL1_ASPFC ;
DR   B8N195, XYL1_ASPFN ;  Q4WJT9, XYL1_ASPFU ;  A2Q8B5, XYL1_ASPNC ;
DR   Q9P8R5, XYL1_ASPNG ;  Q2UKD0, XYL1_ASPOR ;  Q0CUL0, XYL1_ASPTN ;
DR   Q8X195, XYL1_CANBO ;  Q6Y0Z3, XYL1_CANPA ;  O74237, XYL1_CANTE ;
DR   O13283, XYL1_CANTR ;  Q5BGA7, XYL1_EMENI ;  P49378, XYL1_KLULA ;
DR   A1D4E3, XYL1_NEOFI ;  P78736, XYL1_PACTA ;  O94735, XYL1_PICGU ;
DR   P31867, XYL1_PICST ;  G4N708, XYL1_PYRO7 ;  Q9P430, XYL1_SCHSH ;
DR   P87039, XYL2_CANTR ;
//