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ENZYME entry: EC 1.1.1.310

Accepted Name
(S)-sulfolactate dehydrogenase.
Alternative Name(s)
(2S)-3-sulfolactate dehydrogenase.
Reaction catalysed
(2S)-3-sulfolactate + NAD(+) <=> 3-sulfopyruvate + NADH
Comment(s)
  • This enzyme, isolated from the bacterium Chromohalobacter salexigens DSM 3043, acts only on the (S)-enantiomer of 3-sulfolactate.
  • Combined with EC 1.1.1.338, it provides a racemase system that converts (2S)-3-sulfolactate to (2R)-3-sulfolactate, which is degraded further by EC 4.4.1.24.
  • The enzyme is specific for NAD(+).
Cross-references
PROSITEPDOC00063
BRENDA1.1.1.310
EC2PDB1.1.1.310
ExplorEnz1.1.1.310
PRIAM enzyme-specific profiles1.1.1.310
KEGG Ligand Database for Enzyme Nomenclature1.1.1.310
IUBMB Enzyme Nomenclature1.1.1.310
IntEnz1.1.1.310
MEDLINEFind literature relating to 1.1.1.310
MetaCyc1.1.1.310
Rhea expert-curated reactions1.1.1.310
UniProtKB/Swiss-Prot
P16142, MDH_METFV;  Q1QWN6, SLCC_CHRSD;  

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