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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.1.1.324

Accepted Name
8-hydroxygeraniol dehydrogenase.
Alternative Name(s)
8-hydroxygeraniol oxidoreductase.
CYP76B10.
Reaction catalysed
(6E)-8-hydroxygeraniol + 2 NADP(+) <=> (6E)-8-oxogeranial + 2 NADPH
Cofactor(s)
Zn(2+).
Comment(s)
  • The enzyme catalyzes the oxidation of (6E)-8-hydroxygeraniol to (6E)- 8-oxogeranial via either (6E)-8-hydroxygeranial or (6E)-8- oxogeraniol.
  • Also acts on geraniol, nerol and citronellol.
  • May be identical to EC 1.1.1.183.
  • The recommended numbering of geraniol gives 8-hydroxygeraniol as the substrate rather than 10-hydroxygeraniol.
Cross-references
BRENDA1.1.1.324
EC2PDB1.1.1.324
ExplorEnz1.1.1.324
PRIAM enzyme-specific profiles1.1.1.324
KEGG Ligand Database for Enzyme Nomenclature1.1.1.324
IUBMB Enzyme Nomenclature1.1.1.324
IntEnz1.1.1.324
MEDLINEFind literature relating to 1.1.1.324
MetaCyc1.1.1.324
UniProtKB/Swiss-Prot
Q6V4H0, 10HGO_CATRO

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