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ENZYME

ENZYME entry: EC 1.1.1.329

Accepted Name
2-deoxy-scyllo-inosamine dehydrogenase
Reaction catalysed
  • 2-deoxy-scyllo-inosamine + NADP(+) <=> 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADPH
  • 2-deoxy-scyllo-inosamine + NAD(+) <=> 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADH
Comment(s)
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, neomycin and ribostamycin. cf. EC 1.1.99.38.
Cross-references
BRENDA1.1.1.329
EC2PDB1.1.1.329
ExplorEnz1.1.1.329
PRIAM enzyme-specific profiles1.1.1.329
KEGG Ligand Database for Enzyme Nomenclature1.1.1.329
IUBMB Enzyme Nomenclature1.1.1.329
IntEnz1.1.1.329
MEDLINEFind literature relating to 1.1.1.329
MetaCyc1.1.1.329
Rhea expert-curated reactions1.1.1.329
UniProtKB/Swiss-Prot
Q70KF0, DOIAD_MICECQ2MFP3, DOIAD_STREYQ53U21, DOIAD_STRFR
Q6L743, DOIAD_STRKNQ2MF72, DOIAD_STRLVQ4R0W1, DOIAD_STRRI
Q2MF22, DOIAD_STRSD

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