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ENZYME entry: EC 1.1.1.333

Accepted Name
Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase.
Alternative Name(s)
Decaprenylphospho-beta-D-ribofuranose 2'-epimerase.
Reaction catalysed
Trans,octacis-decaprenylphospho-beta-D-arabinofuranose + NAD(+) <=> trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + NADH
Comment(s)
  • The reaction is catalyzed in the reverse direction.
  • The enzyme, isolated from the bacterium Mycobacterium smegmatis, is involved, along with EC 1.1.98.3, in the epimerization of trans,octacis-decaprenylphospho-beta-D-ribofuranose to trans,octacis- decaprenylphospho-beta-D-arabinoofuranose, the arabinosyl donor for the biosynthesis of mycobacterial cell wall arabinan polymers.
Cross-references
BRENDA1.1.1.333
EC2PDB1.1.1.333
ExplorEnz1.1.1.333
PRIAM enzyme-specific profiles1.1.1.333
KEGG Ligand Database for Enzyme Nomenclature1.1.1.333
IUBMB Enzyme Nomenclature1.1.1.333
IntEnz1.1.1.333
MEDLINEFind literature relating to 1.1.1.333
MetaCyc1.1.1.333
Rhea expert-curated reactions1.1.1.333
UniProtKB/Swiss-Prot
P66784, DPRE2_MYCBO;  A0R610, DPRE2_MYCS2;  P9WGS8, DPRE2_MYCTO;  
P9WGS9, DPRE2_MYCTU;  

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