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ENZYME entry: EC 1.1.1.337
Accepted Name |
L-2-hydroxycarboxylate dehydrogenase (NAD(+)).
|
Alternative Name(s) |
(R)-sulfolactate dehydrogenase. |
L-2-hydroxyacid dehydrogenase (NAD(+)). |
L-sulfolactate dehydrogenase. |
Reaction catalysed |
a (2S)-2-hydroxycarboxylate + NAD(+) <=> a 2-oxocarboxylate + H(+) + NADH |
Comment(s) |
- The enzyme from the archaeon Methanocaldococcus jannaschii acts on
multiple L-2-hydroxycarboxylates including (2R)-3-sulfolactate, (S)-
malate, (S)-lactate, and (S)-2-hydroxyglutarate.
- Note that (2R)-3-sulfolactate has the same stereo configuration as
(2S)-2-hydroxycarboxylates.
|
Cross-references |
BRENDA | 1.1.1.337 |
EC2PDB | 1.1.1.337 |
ExplorEnz | 1.1.1.337 |
PRIAM enzyme-specific profiles | 1.1.1.337 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.337 |
IUBMB Enzyme Nomenclature | 1.1.1.337 |
IntEnz | 1.1.1.337 |
MEDLINE | Find literature relating to 1.1.1.337 |
MetaCyc | 1.1.1.337 |
Rhea expert-curated reactions | 1.1.1.337 |
UniProtKB/Swiss-Prot |
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