ID 1.1.1.343 DE phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating). AN 6-PGDH. CA 6-phospho-D-gluconate + NAD(+) = CO2 + D-ribulose 5-phosphate + NADH. CC -!- Highly specific for NAD(+). CC -!- The enzyme catalyzes both the oxidation and decarboxylation of CC 6-phospho-D-gluconate. CC -!- In the bacterium Methylobacillus flagellatus the enzyme participates CC in a formaldehyde oxidation pathway. cf. EC 1.1.1.44. DR P12013, 6PGDH_BACSU; G5EBD7, 6PGDH_GLUOX; D4GST8, 6PGD_HALVD ; //